David E. Bergbreiter

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Aqueous processes ranging from protein folding and enzyme turnover to colloidal ordering and macromolecular precipitation are sensitive to the nature and concentration of the ions present in solution. Herein, the effect of a series of sodium salts on the lower critical solution temperature (LCST) of poly(N-isopropylacrylamide), PNIPAM, was investigated with(More)
Terminally vinyl-functionalized polyisobutylene (PIB) oligomers can be easily transformed into end-functionalized PIB-bound Ru metathesis catalysts. The nonpolar catalysts so prepared can be used as solutions in heptane and recycled by a gravity-based extraction after addition of a heptane-immiscible polar solvent. This paper describes the synthesis and the(More)
The effect of a series of sodium salts on the lower critical solution temperature (LCST) of poly(N-isopropylacrylamide), PNIPAM, was investigated as a function of molecular weight and polymer concentration with a temperature gradient microfluidic device under a dark-field microscope. In solutions containing sufficient concentrations of kosmotropic anions,(More)
In this paper we show that hyperbranched polymers can be used as a host matrix for electrostatic entrapment of enzymes. Specifically, amine-functionalized glucose oxidase (GOx+) and horseradish peroxidase, as well as poly(amidoamine) dendrimer-modified horseradish peroxidase, reversibly sorb into polyanionic, hyperbranched poly(sodium acrylate) (PAA-) films(More)
The use of polymers other than divinylbenzene crosslinked polystyrene as supports in organic chemistry is discussed. Insoluble polymer alternatives to DVB crosslinked polystyrene discussed include porous polyethylene supports, polymer-supported functional colloids, micron and submicron-sized particles and hollow spheres and one-dimensional supports. Soluble(More)
[Structure: see text] The synthesis and characterization of thermoresponsive, water-soluble poly-N-isopropyl acrylamide (PNIPAM) derived macroligands displaying cyclosporin A (CsA) and dexamethasone (Dex) for use as novel affinity resins are described. Characterization of these soluble macroligands, including ligand loading and integrity, was determined by(More)
The preparation of polyethylene-oligomer (PE(olig))-supported N-heterocyclic carbene ligands (NHCs) and their Ru complexes is described. These complexes are structurally analogous to their low molecular weight counterparts and can serve as thermomorphic, recoverable/recyclable ring-closing metathesis (RCM) catalysts. Because of the insolubility of(More)
Fatty acid esters have been synthesized in good yield by reaction between copper(I) ate complexes formed from methylcopper(I) and primary or secondary Grignard reagents and esters of primary iodoalkylcarboxylic acids. The synthetic method is i l lustrated with proced.ures for CHr:gH(CHz)rgCO2C2H5, CeHsCHzO(CH2)16COzCzHs, CH3(CH2)25CO2C2H5,(More)