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In vitro, engagement of GITR on Treg cells by the agonistic anti-GITR mAb, DTA-1, appears to abrogate their suppressive function. The consequence of in vivo engagement of GITR by DTA-1 is, however,… Continue Reading
S. The compounds of this invention may be prepared by two general methods. Condensation of two moles of an aromatic hydrocarbon with a fluoroketone in the presence of hydrogen fluoride or by… Continue Reading