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  • David Coe, Shaima Begom, Caroline V. P. Addey, Matthew L. J. White, Julian P. Dyson, Jian-Guo Chai
  • Medicine, Biology
  • Cancer Immunology, Immunotherapy
  • 2010 (First Publication: 1 September 2010)
  • In vitro, engagement of GITR on Treg cells by the agonistic anti-GITR mAb, DTA-1, appears to abrogate their suppressive function. The consequence of in vivo engagement of GITR by DTA-1 is, however,Continue Reading
    S. The compounds of this invention may be prepared by two general methods. Condensation of two moles of an aromatic hydrocarbon with a fluoroketone in the presence of hydrogen fluoride or byContinue Reading