David C. Miller

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Presents a novel synthesis procedure to realize an associative memory using the Generalized-Brain-State-in-a-Box (GBSB) neural model. The implementation yields an interconnection structure that guarantees that the desired memory patterns are stored as asymptotically stable equilibrium points and that possesses very few spurious states. Furthermore, the(More)
A detailed implementation of the Tabu Search (TS) algorithm for computer-aided molecular design (CAMD) of transition metal catalysts is presented in this paper. Previous CAMD research has applied deterministic methods or genetic algorithms to the solution of the optimization problems which arise from the search for a molecule satisfying a set of property(More)
PURPOSE Osteoarthritis (OA) is a degenerative disease starting with key molecular events that ultimately lead to the breakdown of the cartilage. The purpose of this study is to use two imaging methods that are sensitive to molecular and macromolecular changes in OA to better characterize the disease process in human osteoarthritic cartilage. PROCEDURES(More)
BACKGROUND Unlike other malignancies, there is no literature supporting the accuracy of medical claims data for identifying surgical treatments among patients with kidney cancer. We sought to validate externally a previously published Medicare-claims-based algorithm for classifying surgical treatments among patients with early-stage kidney cancer. To(More)
We examined the overall survival of a population-based cohort of black and white patients with renal cell carcinoma (RCC) to better understand the paradox of poorer RCC survival despite more frequent diagnosis at lower stage among blacks. Renal cell carcinoma patients (699 white, 252 black) diagnosed between 2002 and 2007 in metropolitan Detroit were(More)
Determining the minimum number of units is an important step in heat exchanger network synthesis (HENS). The MILP transshipment model (Papoulias and Grossmann, 1983) and transportation model (Cerda and Westerberg, 1983b) were developed for this purpose. However, they are computationally expensive when solving for large-scale problems. Several approaches are(More)