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BACKGROUND Findings from several studies support the conclusion that spermatozoa contain a complex repertoire of mRNAs. Even though these mRNAs are thought to provide an insight into past events of spermatogenesis, their complexity and function have yet to be established. Our aim was to determine whether we could use spermatozoal mRNAs to generate a genetic(More)
Even though the genetic fingerprint of human sperm has been defined, its role in orchestrating fertilization and the development of the early embryo remains vague. Here we show that human male gametes pass over more to the oocyte than just the haploid male genome--paternal messenger RNAs are also delivered to the egg at fertilization. If these transcripts,(More)
This paper investigates a new class of 2-player games in continuous time, in which the players' observations of each other's actions are distorted by Brownian motions. These games are analogous to repeated games with imperfect monitoring in which the players take actions frequently. Using a differential equation we find the set E(r) of payoff pairs(More)
Thirty-four matched pairs of sixth-and seventh-grade students were selected from 358 participants in a comparison of an explicit concrete-to-representational-to-abstract (CRA) sequence of instruction with traditional instruction for teaching algebraic transformation equations. Each pair of students had been previously labeled with a specific learning(More)
During the haploid phase of mammalian spermatogenesis, nucleosomal chromatin is ultimately repackaged by small, highly basic protamines to generate an extremely compact, toroidal chromatin architecture that is critical to normal spermatozoal function. In common with several species, however, the human spermatozoon retains a small proportion of its chromatin(More)
Presents a novel synthesis procedure to realize an associative memory using the Generalized-Brain-State-in-a-Box (GBSB) neural model. The implementation yields an interconnection structure that guarantees that the desired memory patterns are stored as asymptotically stable equilibrium points and that possesses very few spurious states. Furthermore, the(More)
Fully automated 300mm manufacturing requires the adoption of a real-time lot dispatching paradigm. Automated dispatching has provided significant improvements over manual dispatching by removing variability from the thousands of dispatching decisions made every day in a fab. Real-time resolution of tool queues, with consideration of changing equipment(More)
The National Center for Education Statistics (NCES) is the primary federal entity for collecting, analyzing, and reporting data related to education in the United States and other nations. It fulfills a congressional mandate to collect, collate, analyze, and report full and complete statistics on the condition of education in the United States; conduct and(More)
Determining the minimum number of units is an important step in heat exchanger network synthesis (HENS). The MILP transshipment model (Papoulias and Grossmann, 1983) and transportation model (Cerda and Westerberg, 1983b) were developed for this purpose. However, they are computationally expensive when solving for large-scale problems. Several approaches are(More)
CONTEXT The cognitive side effects of medications with anticholinergic activity have been documented among older adults in a variety of clinical settings. However, there has been no systematic confirmation that acute or chronic prescribing of such medications lead to transient or permanent adverse cognitive outcomes. OBJECTIVE Evaluate the existing(More)