David C. Howell

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This study assessed anxiety/depression and stress response symptoms in adult cancer patients (n = 117), spouses (n = 76), and their children (n = 110, ages 6 to 30 years old) near the patients' diagnoses to identify family members at risk for psychological maladjustment. Patients' and family members' distress was related to appraisals of the seriousness and(More)
Payne and Jones (1957) presented a useful formula for estimating the abnormality of differences between an individual's scores on two tests. Extending earlier work by Sokal and Rohlf (1995) and Crawford and Howell (in press), we developed a modified paired samples t test as an alternative to this formula. Unlike the Payne and Jones formula, the new method(More)
Corballis [Corballis, M. C. (2009). Comparing a single case with a control sample: Refinements and extensions. Neuropsychologia] offers an interesting position paper on statistical inference in single-case studies. The following points arise: (1) Testing whether we can reject the null hypothesis that a patient's score is an observation from the population(More)
Regression equations are widely used in clinical neuropsychology, particularly as an alternative to conventional normative data. In neuropsychological applications the most common method of making inferences concerning the difference between an individual's test score and the score predicted by a regression equation is to multiply the standard error of(More)
Activation of the coagulation cascade is commonly observed in the lungs of patients with both acute and chronic inflammatory and fibrotic lung disorders, as well as in animal models of these disorders. The aim of this study was to examine the contribution of the major thrombin receptor, proteinase-activated receptor-1 (PAR-1), during the acute inflammatory(More)
Cognitive appraisals and coping were examined in children, adolescents, and young adults (N = 134) faced with the diagnosis of cancer in a parent. All 3 age groups perceived low personal control and high external control over their parent's illness and used relatively little problem-focused coping. Adolescents and young adults reported more emotion-focused(More)
Performance on some neuropsychological tests is best expressed as an intra-individual measure of association (such as a parametric or non-parametric correlation coefficient or the slope of a regression line). Examples of the use of intra-individual measures of association (IIMAs) include the quantification of performance on tests designed to assess temporal(More)
INTRODUCTION There is growing evidence of poor mental health and quality of life among survivors of intensive care. However, it is not yet clear to what extent the trauma of life-threatening illness, associated drugs and treatments, or patients' psychological reactions during intensive care contribute to poor psychosocial outcomes. Our aim was to(More)
We examined attributions of behavioral and characterological self-blame and perceptions of control over disease progression and recurrence as predictors of symptoms of psychological distress in a sample of adult men and women with cancer. Data were obtained near the time of diagnosis and at 4-month follow-up. Initial levels of behavioral and(More)
The use of allogeneic haematopoietic stem cell transplantation (Allo-HSCT) is a standard treatment option for many patients with haematological malignancies. Historically, patients requiring intensive care unit (ICU) admission for transplant-related toxicities have fared extremely poorly, with high ICU mortality rates. Little is known about the impact of(More)