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Planar cell polarity signaling in Drosophila requires the receptor Frizzled and the cytoplasmic proteins Dishevelled and Prickle. From initial, symmetric subcellular distributions in pupal wing… (More)
- Damian C Crowther, Kerri J Kinghorn, +5 authors Debra A. Lomas
- Neuroscience
- 2005
We have developed models of Alzheimer's disease in Drosophila melanogaster by expressing the Abeta peptides that accumulate in human disease. Expression of wild-type and Arctic mutant (Glu22Gly)… (More)
- David C Gubb, Aran Garcia-Bellido
- Journal of embryology and experimental morphology
- 1982
The polarity mutants pk, sple, mwh, fz and in alter the orientations of cuticular processes in several regions of the body. The mutant polarity patterns are constant and do not result from… (More)
- David C Gubb, C. Green, +5 authors John Roote
- Genes & development
- 1999
The tissue polarity mutants in Drosophila include a set of conserved gene products that appear to be involved in the control of cytoskeletal architecture. Here we show that the tissue polarity gene… (More)
- J. Chae, M. J. Kim, +5 authors W. J. Park
- Development
- 1999
The tissue polarity genes control the polarity of hairs, bristles and ommatidia in the adult epidermis of Drosophila. We report here the identification of a new tissue polarity gene named starry… (More)
- Elena A Levashina, Elizabeth J Langley, +4 authors Jean - Marc Reichhart
- Science
- 1999
The antifungal defense of Drosophila is controlled by the spaetzle/Toll/cactus gene cassette. Here, a loss-of-function mutation in the gene encoding a blood serine protease inhibitor, Spn43Ac, was… (More)
- Edward J. Ryder, Fiona M. Blows, +34 authors Steven Russell
- Genetics
- 2004
We describe a collection of P-element insertions that have considerable utility for generating custom chromosomal aberrations in Drosophila melanogaster. We have mobilized a pair of engineered P… (More)
- Alex Wilkins, David C Gubb
- Developmental biology
- 1991
- Jie Yan, David S. Huen, +4 authors Paul N Adler
- Genetics
- 2008
The frizzled signaling/signal transduction pathway controls planar cell polarity (PCP) in both vertebrates and invertebrates. Epistasis experiments argue that in the Drosophila epidermis multiple… (More)
- Edward J. Ryder, Michael Ashburner, +34 authors Steven Russell
- Genetics
- 2007
We describe a second-generation deficiency kit for Drosophila melanogaster composed of molecularly mapped deletions on an isogenic background, covering approximately 77% of the Release 5.1 genome.… (More)