David Buchanan

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The possibility that alexithymia respresents a symptom of subtle brain dysfunction is discussed. Several lines of research have shown that emotional thought, behavior and, in particular, the use of affect-laden speech are influenced by impaired function of the right hemisphere or a disconnection between the two hemispheres. A patient with agenesis of the(More)
Twenty-five families were interviewed to examine their adjustments to having a child with Duchenne muscular dystrophy (DMD). Chronic emotional stress experienced by families of DMD children was found to be a significant problem in the overall management of the illness. Based on information obtained from the assessment of families' adaptation to their(More)
BACKGROUND Intravenous recombinant tissue plasminogen activator (rtPA) is approved in Europe for use in patients with acute ischaemic stroke who meet strictly defined criteria. IST-3 sought to improve the external validity and precision of the estimates of the overall treatment effects (efficacy and safety) of rtPA in acute ischaemic stroke, and to(More)
Eleven boys with Duchenne's muscular dystrophy, randomly assigned to placebo (group A, n = 6) or penicillamine treatment (group B, n = 5), received three capsules per day containing lactose or 250 mg of penicillamine. All patients received pyridoxine, 50 mg daily. Mean age at entrance into study was similar for both groups (group A , 86.7 +/- 31.6 months;(More)
The cephalometric measurement known as Wits appraisal (AOBO) was studied to determine its importance in diagnosis, treatment, and prediction of treatment success. The Wits appraisal is used primarily to identify unreliable ANB values (those that do not accurately reflect the degree of horizontal jaw discrepancy, ie, those that differ greatly from the AOBO(More)
The literature on psychological reactions to renal transplantation in adult donors and recipients is reviewed. Although the psychiatric complications of kidney transplantation appear to be fewer than in renal dialysis, the operation represents a threat to the donor, recipient and extended family. Donors, despite altruistic motivations for offering their(More)
Prosthetic valve thrombosis is rare; its complication by coronary embolism is even more uncommon and when present, often fatal. Here, we present a rare case of mechanical aortic valve thrombosis with coronary emboli presenting in cardiogenic shock, managed successfully using a hybrid approach of mechanical thrombectomy and intravenous fibrinolytic therapy.