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OBJECTIVE To investigate the association between social circumstances in childhood and mortality from various causes of death in adulthood. DESIGN Prospective observational study. SETTING 27 workplaces in the west of Scotland. SUBJECTS 5645 men aged 35-64 years at the time of examination. MAIN OUTCOME MEASURES Death from various causes. RESULTS(More)
Recent interest in a lifecourse perspective on health inequalities will rekindle concerns about the accuracy of retrospective data. The present paper demonstrates that recalled information on some types of social circumstances can be obtained with a useful degree of accuracy using an interview technique which helps to minimize recall bias. Lifegrid(More)
BACKGROUND To analyse whether Adverse Childhood Experiences (ACE) are associated with an increased risk of cancer. METHODS The National child development study (NCDS) is a prospective birth cohort study with data collected over 50 years. The NCDS included all live births during one week in 1958 (n=18558) in Great Britain. Self-reported cancer incidence(More)
Events causing stress responses during sensitive periods of rapid neurological development in childhood may be early determinants of all-cause premature mortality. Using a British birth cohort study of individuals born in 1958, the relationship between adverse childhood experiences (ACE) and mortality≤50 year was examined for men (n=7,816) and women(More)
We examined the influences of childhood social background, childhood cognitive ability, and education on intergenerational social mobility and social status attainment at midlife. The subjects were men born in 1921 and who participated in the Scottish Mental Survey of 1932 and thereafter in the Midspan Collaborative study in Scotland between 1970 and 1973.(More)
OBJECTIVES To determine the extent to which secondary drug prevention for patients with stroke in routine primary care varies by sex, age, and socioeconomic circumstances, and to quantify the effect of secondary drug prevention on one year mortality by sociodemographic group. DESIGN Cohort study using individual patient data from the health improvement(More)
This mixed-methods study looks at the relationship between adversity and resilience. It examines the dynamics of protection in a sub-sample of the Boyd Orr cohort that are aged between 70 and 80 years of age (n = 139). We used a questionnaire and activity diaries to gather a range of quantitative data, and interviews using lifegrids to explore past and(More)
Tooth development is a highly heritable process which relates to other growth and developmental processes, and which interacts with the development of the entire craniofacial complex. Abnormalities of tooth development are common, with tooth agenesis being the most common developmental anomaly in humans. We performed a genome-wide association study of time(More)
OBJECTIVE To investigate if unemployment during an economic downturn is associated with mortality, even among men with markers of better health (higher cognitive function scores and qualifications), and to assess whether the associations vary by age at unemployment. DESIGN Longitudinal register-based cohort study. SETTING Study entry was in 1990 and(More)
INTRODUCTION Considerable evidence suggests that patients with more advantaged Socio-Economic Positions undergo Total Hip and Knee Replacement (THR/TKR) more often, despite having a lower need. We questioned whether more disadvantaged Socio-Economic Position is associated with an lower improvement in Health-Related Quality of Life (HRQoL) and a lower(More)