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G-protein-coupled receptors signalling at the cell nucleus: an emerging paradigm.

• Fernand Gobeil, Audrey Fortier, +7 authors David Barbaz
• Canadian journal of physiology and pharmacology
• 2006

G-protein-coupled receptors (GPCRs) comprise a wide family of monomeric heptahelical glycoproteins that recognize a broad array of extracellular mediators including cationic amines, lipids, peptides,… (More)

Expression of endogenous nuclear bradykinin B2 receptors mediating signaling in immediate early gene activation.

• Martin Savard, David Barbaz, +6 authors Fernand Gobeil
• Journal of cellular physiology
• 2008

Bradykinin (BK) represents a pro-inflammatory mediator that partakes in many inflammatory diseases. The mechanism of action of BK is thought to be primarily mediated by specific cell surface membrane… (More)

Nitric oxide signaling via nuclearized endothelial nitric-oxide synthase modulates expression of the immediate early genes iNOS and mPGES-1.

• Fernand Gobeil, Tang Zhu, +17 authors Sylvain Chemtob
• The Journal of biological chemistry
• 2006

Stimulation of freshly isolated rat hepatocytes with lysophosphatidic acid (LPA) resulted in LPA1 receptor-mediated and nitricoxide-dependent up-regulation of the immediate early genes iNOS… (More)

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