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BACKGROUND Phages, viruses that infect prokaryotes, are the most abundant microbes in the world. A major limitation to studying these viruses is the difficulty of cultivating the appropriate prokaryotic hosts. One way around this limitation is to directly clone and sequence shotgun libraries of uncultured viral communities (i.e., metagenomic analyses).(More)
Metagenomic analyses suggest that the rank-abundance curve for marine phage communities follows a power law distribution. A new type of power law dependence based on a simple model in which a modified version of Lotka-Volterra predator-prey dynamics is sampled uniformly in time is presented. Biologically, the model embodies a kill the winner hypothesis and(More)
Phage are the most abundant biological entities in the biosphere, with an estimated 10 31 particles on the planet. They also play a major role in carbon cycling; at least 25% of fixed carbon passes through phage. Their roles as predators of bacteria have important implications for possible marine CO 2 sequestration. Metagenomic analyses show that the(More)
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