Schnyder crystalline corneal dystrophy (SCCD, MIM 121800) is a rare autosomal dominant disease characterized by progressive opacification of the cornea resulting from the local accumulation of lipids, and associated in some cases with systemic dyslipidemia. Although previous studies of the genetics of SCCD have localized the defective gene to a 1.58 Mbp… (More)
The vast expansion of international nancial activity over the last decade has been a central fact of international economic life. Balance-of-payments statistics indicate that cross-border transactions in bonds and equities among the G-7 countries rose from less than 10 percent of gross domestic product (GDP) in 1980 to over 140 percent in 1995. 1… (More)
Newborns with peripheral nerve lesions involving the upper extremity are difficult to evaluate. The reliability of the Active Movement Scale (AMS), a tool for assessing motor function in infants with obstetrical brachial plexus palsy (OBPP), was examined in 2 complementary studies. Part A was an interrater reliability study in which 63 infants younger than… (More)
Spontaneous apoptosis of T lymphocytes results in marked lymphopenia in the Biobreeding diabetes-prone (BB-DP) rat leading to the development of autoimmune type 1 diabetes. The lymphopenia phenotype in these rats is linked to the lyp locus. The lyp allele harbors a frameshift mutation within the gene encoding 'GTPase of immunity-associated nucleotide… (More)
Plasma ropivacaine levels produced by routine scalp infiltration for field block were assayed in eight patients undergoing awake intracranial surgery. Levels peaked within approximately 13 minutes, indicating rapid systemic absorption of ropivacaine. Potentially toxic plasma drug levels were achieved in three of eight patients, although no untoward effects… (More)
We examine why these regulatory differences exist and what they imply for differences in minimum capital requirements for position risk. We consider differences in the definition and measurement of regulatory capital and we quantify differences in the capital charges for position risk by reference to a model portfolio that contains a variety of financial… (More)
In this paper, we discuss how the evolution of embedded systems has impacted on the design and usage of Real-Time Operating Systems (RTOS). Specifically, we consider issues that result from the integration of complex requirements for embedded systems. Integration has been identified as a complex issue in various fields such as automotive, critical systems… (More)
and several economists at the IMF who should perhaps best remain anonymous.
for discussion of these ideas. David Andrews can be credited for having introduced this topic at an early point, whilst Uta Frith and Franky Happe can be credited for their influential notion of 'cognitive style'. Finally, Dante Cicchetti and Alan Sroufe provided excellent editorial advice.
Field Programmable Gate Arrays (FPGAs) can be customized into application-specific architectures to achieve high performance and energy-efficiency. Unfortunately, they are yet to gain significant adoption by application developers due to their low-level programming model. Moreover, to obtain good performance in an FPGA design, one often needs to correctly… (More)