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Psychrophilic (cold-adapted) organisms and their products have potential applications in a broad range of industrial, agricultural and medical processes. In order for growth to occur in low-temperature environments, all cellular components must adapt to the cold. This fact, in combination with the diversity of Archaea, Bacteria and Eucarya isolated from(More)
Schnyder crystalline corneal dystrophy (SCCD, MIM 121800) is a rare autosomal dominant disease characterized by progressive opacification of the cornea resulting from the local accumulation of lipids, and associated in some cases with systemic dyslipidemia. Although previous studies of the genetics of SCCD have localized the defective gene to a 1.58 Mbp(More)
Education and training in transfusion medicine have improved over the past decade in developing countries but are still generally deficient for the purpose of maintaining the safety of the global blood supply. In 2009, the World Health Organization global database on blood safety indicated that only 72% of countries in the world were able to meet their(More)
Spontaneous apoptosis of T lymphocytes results in marked lymphopenia in the Biobreeding diabetes-prone (BB-DP) rat leading to the development of autoimmune type 1 diabetes. The lymphopenia phenotype in these rats is linked to the lyp locus. The lyp allele harbors a frameshift mutation within the gene encoding 'GTPase of immunity-associated nucleotide(More)
In this paper, we discuss how the evolution of embedded systems has impacted on the design and usage of Real-Time Operating Systems (RTOS). Specifically, we consider issues that result from the integration of complex requirements for embedded systems. Integration has been identified as a complex issue in various fields such as automotive, critical systems(More)
OBJECTIVE To develop and implement a service model for people with spinal cord injury (SCI) living in rural regions. DESIGN Service development, pilot evaluation study. SETTING Regional and remote areas of the state of New South Wales, Australia. PARTICIPANTS Persons with SCI, caregivers, and health professionals. INTERVENTION Phase 1 included(More)
We examine why these regulatory differences exist and what they imply for differences in minimum capital requirements for position risk. We consider differences in the definition and measurement of regulatory capital and we quantify differences in the capital charges for position risk by reference to a model portfolio that contains a variety of financial(More)
Field Programmable Gate Arrays (FPGAs) can be customized into application-specific architectures to achieve high performance and energy-efficiency. Unfortunately, they are yet to gain significant adoption by application developers due to their low-level programming model. Moreover, to obtain good performance in an FPGA design, one often needs to correctly(More)
Substance abuse continues to greatly impact the US population. The purpose of this study is to improve understanding of the reasons why individuals seek substance user treatment. Qualitative interviews were conducted with 50 men (n = 25) and women (n = 25) across eight substance user treatment programs in Durham, North Carolina, in 2010. We identify six(More)