Learn More
Atthe International Workshop on Genotoxicity Test Procedures (IWGTP) held in Washington, DC, March 25-26, 1999, an expert panel met to develop guidelines for the use of the single-cell gel (SCG)/Comet assay in genetic toxicology. The expert panel reached a consensus that the optimal version of the Comet assay for identifying agents with genotoxic activity(More)
Dynamic languages such as JavaScript are more difficult to compile than statically typed ones. Since no concrete type information is available, traditional compilers need to emit generic code that can handle all possible type combinations at runtime. We present an alternative compilation technique for dynamically-typed languages that identifies frequently(More)
Evidence from electrophysiological studies has suggested an inhibitory interaction between GABAergic neurons in substantia nigra pars reticulata and dopaminergic neurons in pars compacta. However, that this inhibitory interaction is due to a projection from pars reticulata to pars compacta has never been demonstrated directly, nor has the GA-BAergic neuron(More)
BACKGROUND The limitations of the current diagnostic standard, ventilation-perfusion lung scanning, complicate the management of patients with suspected pulmonary embolism. We previously demonstrated that determining the pretest probability can assist with management and that the high negative predictive value of certain D -dimer assays may simplify the(More)
BACKGROUND Several diagnostic strategies using ultrasound imaging, measurement of D-dimer, and assessment of clinical probability of disease have proved safe in patients with suspected deep-vein thrombosis, but they have not been compared in randomized trials. METHODS Outpatients presenting with suspected lower-extremity deep-vein thrombosis were(More)
Src homology (SH) regions 2 and 3 are noncatalytic domains that are conserved among a series of cytoplasmic signaling proteins regulated by receptor protein-tyrosine kinases, including phospholipase C-gamma, Ras GTPase (guanosine triphosphatase)-activating protein, and Src-like tyrosine kinases. The SH2 domains of these signaling proteins bind tyrosine(More)
Evidence from electrophysiological studies has suggested an inhibitory interaction between GABAergic neurons in substantia nigra pars reticulata and dopaminergic neurons in pars compacta. However, that this inhibitory interaction is due to a projection from pars reticulata to pars compacta has never been demonstrated directly, nor has the GABAergic neuron(More)
Digital citizen science offers a low-cost way to strengthen the scientific infrastructure, and engage members of the public in science. It is based on two pillars:(1)a technological pillar, which involves developing computer systems to manage large amounts of distributed resources, and (2) a motivational pillar, which involves attracting and retaining(More)
The longer a look at TV is maintained, the conditional probability that it will be further maintained rapidly increases for about 15 sec, after which it increases slowly. This increase in the conditional probability of maintaining a look is called "attentional inertia." An external audiovisual distractor stimulus was presented during 3- and 5-year-olds' TV(More)