David A. Rubin

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A cDNA that codes for the polypeptide hormone precursor proopiomelanocortin (POMC) was cloned and sequenced from a gar (Lepisosteus osseus) pituitary cDNA library. The gar POMC cDNA is 1237 bp and contains a 780-bp open reading frame. The deduced amino acid sequence for gar POMC is 259 amino acids in length. The general organization of gar POMC is very(More)
OBJECTIVE Proponents of femoroacetabular impingement (FAI) now claim that FAI is an important risk factor for hip osteoarthritis and argue that early, aggressive treatment is indicated to stave off long-term complications. The result is more young patients undergoing corrective surgery; does the literature support these claims or has hype trumped reality?(More)
BACKGROUND Syndesmosis ankle sprains cause greater disability and longer duration of recovery than lateral ankle sprains. OBJECTIVE To describe the severity of syndesmosis sprains using several accepted magnetic resonance imaging (MRI) criteria and to assess the interrater reliability of diagnosing syndesmosis injury using these same criteria in(More)
To evaluate the sensitivity of a non-receiver-operating characteristic (ROC) study in assessing small differences of perceived image quality of hand images acquired by computed radiography (CR) and conventional screen-film systems, hand images were acquired on 12 patients with both conventional screen-film and CR. Each CR image was then processed with three(More)
Osteoporosis is a bone disease that commonly results in a 30% incidence of fracture in hens used to produce eggs for human consumption. One of the causes of osteoporosis is the lack of mechanical strain placed on weight-bearing bones. In conventionally-caged hens, there is inadequate space for chickens to exercise and induce mechanical strain on their(More)
The aim of this study is to develop a secure, Google-based data-mining tool for radiology reports using free and open source technologies and to explore its use within an academic radiology department. A Health Insurance Portability and Accountability Act (HIPAA)-compliant data repository, search engine and user interface were created to facilitate(More)