David A. Pickles

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Previous cadaveric studies have suggested that forefoot deformities at the metatarsophalangeal (MTP) joints in patients with rheumatoid arthritis (RA) might result from the failure of the ligamentous system and displacement of the plantar plates. This study aimed to examine the relationship between plantar plate pathology and the rheumatoid arthritis(More)
Introduction Forefoot pain in Rheumatoid Arthritis (RA) is associated with functional and structural changes at the MTP joints. Previous cadaveric studies have suggested that forefoot deformities in RA might result from the failure of a complex ligamentous system and displacement of the plantar plates (PP). MRI and high resolution ultrasound (HRUS) have(More)
Introduction Despite the introduction of more aggressive systemic therapies for the management of rheumatoid arthritis (RA) MTP joint pain & deformity is commonly reported. Previous research has proposed that articular damage in the forefoot of patients with RA is probably caused by synovitis leading to destruction of the bone & soft tissues, which might(More)
BACKGROUND Circadian variation of joint stiffness (morning stiffness) and its impact on functional ability are widely recognised in rheumatoid arthritis. Subsequent within-day variation of walking ability is important due to the increased availability of instrumented gait analysis. This study aimed to quantify diurnal variation of gait in patients with(More)
Results Data were collected on 31 pts with RA (11 M, 20 F) median age of 67 (range 35 to 87), disease duration 10.5y (range 1 to 50), mean BMI 25.9 (std +/5.5 ). Median DAS28 5.39 (IQR 2.11) median HAQ 2.25 (IQR 0.79). The largest difference in GV between time points was the increase from 0hr to 1 hr (20.4% 95%CI 9.7 to 31.2) & 1hr to 3hrs (10.2% 95%CI 2.0(More)
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