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Vitamin C has been a popular medication for preventing the common cold and reducing the severity of cold symptoms for many years. 1-r ' Professor Pauling's recent book on the subject has led to even further use of vitamin C in even larger doses. <; This study was performed to look for a difference in the frequency and severity of colds in a generally(More)
BACKGROUND The best surgical modality for treating chronic periprosthetic hip infections remains controversial, with a lack of randomised controlled studies. The aim of this systematic review is to compare the infection recurrence rate after a single-stage versus a two-stage exchange arthroplasty, and the rate of cemented versus cementless single-stage(More)
In this paper we used detailed simulations of application kernels to show that memory contention can substantially degrade the performance of SPMD computations on large-scale shared-memory multiprocessors. We showed that under row-major allocation, memory contention is due to synchronized access to entire rows of a matrix, rather than simultaneous accesses(More)
Tranexamic acid (TXA) is an antifibrinolytic agent that competitively inhibits the activation of plasminogen to plasmin. It has been shown to reduce blood loss in trauma and other haemorrhagic conditions and has recently been utilised in elective orthopaedic surgery. There are various methods of administering TXA described in the literature. This(More)
BACKGROUND Aerosolization of seafood and subsequent inhalation, during processing is a potential high-risk activity for allergic respiratory disease. OBJECTIVES To quantify total thoracic particulate, protein concentration and specific fish (pilchard, anchovy) antigen concentrations in fish processing plants; to determine the correlation between these(More)
Periprosthetic joint infections following hip and knee arthroplasty are challenging complications for Orthopaedic surgeons to manage. The single-stage exchange procedure is becoming increasingly popular with promising results. At our Institute we have demonstrated favourable or similar outcomes compared to the 'gold-standard' two-stage exchange, and other(More)
The presence of a periprosthetic joint infection (PJI) following knee arthroplasty is devastating to the patient, with significant loss of function and independence, with risk of systemic compromise with sepsis and organ failure, and loss of life. This article reviews the management of knee PJIs, with particular emphasis on the two-stage exchange(More)
BACKGROUND The best surgical modality for treating chronic periprosthetic shoulder infections has not been established, with a lack of randomised comparative studies. This systematic review compares the infection eradication rate and functional outcomes after single- or two-stage shoulder exchange arthroplasty, to permanent spacer implant or resection(More)