David A. Beckman

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BACKGROUND To increase understanding of the relationship between sexual violence and mental illness, the authors assessed the legal histories and psychiatric features of 36 males convicted of sexual offenses. METHOD Thirty-six consecutive male sex offenders admitted from prison, jail, or probation to a residential treatment facility received structured(More)
BACKGROUND The authors' objective was to provide data regarding the demographic, phenomenological, course of illness, associated psychiatric and medical comorbidity, family history, and psychiatric treatment response characteristics of rigorously diagnosed subjects who met DSM-IV criteria for intermittent explosive disorder. METHOD Twenty-seven subjects(More)
BACKGROUND The oral administration of d,l-methylphenidate (MPH) was designed to encompass the major part of postnatal development in the rat and to evaluate potential chronic effects. METHODS Wistar Hannover rats were cross-fostered on postpartum day 0 (day of birth) and were administered MPH at doses of 5, 50, and 100 mg/kg/day (mpkd) on postpartum days(More)
Red cell survival, ferrokinetics, and hematologic parameters were investigated in Beagle dogs exposed to chronic hypergravity (2.6 Gx). Ineffective erythropoiesis, red cell mass, plasma volume, and 51 Cr elution were significantly increased; maximum 59Fe incorporation was decreased; and there was no change in the mean erythrocyte life span following(More)
In 1961 we reported that heterologous antisera prepared in the rabbit against rat kidney proved to be teratogenic when injected into pregnant rats (Brent et al, Proc. Soc. Exp. Biol. Med.). The teratogenic antiserum localized in the yolk sac and yolk sac antisera proved to be a potent rat teratogen. Metabolic studies have indicated that the yolk sac(More)
The safety of cysteamine after renal transplantation and during pregnancy is an important issue, since girls with cystinosis are in better health on cysteamine therapy and thus more likely to become pregnant. In the first study, cysteamine was given to pregnant rats on days 6.5–18.5 post conception in oral doses of 0, 37.5, 75, 100, and 150 mg/kg per day.(More)
Juvenile rat toxicity studies with the direct renin inhibitor aliskiren were initiated to support treatment in the pediatric population. In Study 1, aliskiren was administered orally to juvenile rats at doses of 0, 30, 100 or 300 mg/kg/day with repeated dosing from postpartum day (PPD) 8 to PPD 35/36. In-life, clinical pathology, anatomic pathology, and(More)
The IEA Bioenergy Techno-Economic Analysis Activity reported here, had the following objectives: • To assist companies working with technologies and products related to bioenergy applications in their efforts to demonstrate these, • To promote bioenergy technologies, processes and applications, • To built and maintain a network for R&D organisations and(More)