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PTEN genomic deletions that characterize aggressive prostate cancer originate close to segmental duplications
- M. Yoshimoto, O. Ludkovski, +6 authors J. Squire
- Biology, Medicine
- Genes, chromosomes & cancer
- 1 February 2012
Deletion of PTEN at 10q23.3 occurs in ∼40% of human prostate cancers and is associated with aggressive metastatic potential, poor prognosis, and androgen‐independence. This high frequency of… Expand