Dave A. Chokshi

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April 2007 | Volume 4 | Issue 4 | e95 Genomic research has the potential to improve global health by elucidating basic mechanisms of disease, susceptibility, and resistance, thereby guiding the development of preventive interventions [1]. Recently developed methods for exploring how human genetic variation affects resistance are likely to provide strategic(More)
I the face of persistently lackluster job creation, the U.S. health sector is paradoxically seen as both a contributor to torpid macroeconomic growth and a source of local employment opportunities. Labor costs account for more than half of U.S. health care spending, but as payment structures shift from volumebased reimbursement to the rewarding of value in(More)
295 Patient-Assessment-Instruments/Quality Measures/Downloads/NationalImpact AssessmentofQualityMeasuresFINAL.pdf). 2. Martin AB, Lassman D, Washington B, Catlin A. Growth In US health spending remained slow in 2010; health share of gross domestic product was unchanged from 2009. Health Aff (Millwood) 2012;31:208-19. 3. Jha AK, Joynt KE, Orav EJ, Epstein(More)
The Affordable Care Act made admirable strides toward the "triple aim" of reducing health care costs, increasing health care quality, and improving the health of the community at large. A key element of reform is the accountable care organization (ACO), which restructures health care delivery such that networks of providers are held responsible for a group(More)
June 2006 | Volume 3 | Issue 6 | e136 According to the World Health Organization, about 10 million people—most of them in lowand middle-income countries—die needlessly every year because they do not have access to existing medicines and vaccines [1]. Countless others suffer from neglected tropical diseases, such as sleeping sickness, lymphatic fi lariasis,(More)
became public. For example, responding to the Senate report, Vice President Dick Cheney said rectal feeding was not approved but that he believed “it was done for medical reasons.” It seems more accurate to describe rectal feeding as a technique of sexual assault. Seen in the context of the constant state of nudity of most black-site prisoners, it seems(More)
Genomic epidemiology is a field of research that seeks to improve the prevention and management of common diseases through an understanding of their molecular origins. It involves studying thousands of individuals, often from different populations, with exacting techniques. The scale and complexity of such research has required the formation of research(More)
SCIENCE sciencemag.org N oncommunicable diseases (NCDs)— largely comprising cardiovascular disease, cancer, chronic pulmonary disease, and diabetes—are the most important global health issues of the 21st century, as measured by both mortality and morbidity ( 1, 2). These diseases are as preventable across entire populations as are infectious diseases, but(More)
As comparative effectiveness research becomes a more prominent feature of clinical medicine, investigators and policy makers would do well to seek lessons from prior examples of this type of research. Our analysis of previous examples reveals lessons in three key areas: choice of comparison treatments, time frame of study, and widespread applicability of(More)