Dattesh Shanbhag

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UNLABELLED MR-based attenuation correction is instrumental for integrated PET/MR imaging. It is generally achieved by segmenting MR images into a set of tissue classes with known attenuation properties (e.g., air, lung, bone, fat, soft tissue). Bone identification with MR imaging is, however, quite challenging, because of the low proton density and fast(More)
PURPOSE To investigate proton density (PD)-weighted zero TE (ZT) imaging for morphological depiction and segmentation of cranial bone structures. METHODS A rotating ultra-fast imaging sequence (RUFIS) type ZT pulse sequence was developed and optimized for 1) efficient capture of short T2 bone signals and 2) flat PD response for soft-tissues. An inverse(More)
PURPOSE This study introduces a new hybrid ZTE/Dixon MR-based attenuation correction (MRAC) method including bone density estimation for PET/MRI and quantifies the effects of bone attenuation on metastatic lesion uptake in the pelvis. METHODS Six patients with pelvic lesions were scanned using fluorodeoxyglucose (18F-FDG) in an integrated time-of-flight(More)
MR-guided focused ultrasound (MRgFUS) is a non-invasive method by which tissue is ablated using ultrasound energy focused on a point. The procedure has proven effective for stationary targets (e.g. uterine fibroids) but has not yet been used for liver lesion treatment due to organ motion. We describe a method to compensate for organ motion to enable(More)
Matching the bolus arrival time (BAT) of the arterial input function (AIF) and tissue residue function (TRF) is necessary for accurate pharmacokinetic (PK) modeling of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). We investigated the sensitivity of volume transfer constant ([Formula: see text]) and extravascular extracellular volume(More)
Accurate quantification of positron emission tomography (PET) uptake depends on accurate attenuation correction in reconstruction. Current magnetic resonance-based attenuation correction methods (MRAC) for body PET imaging use a fat/water map derived from a two-echo Dixon magnetic resonance imaging (MRI) sequence, where bone is neglected. Ultrashort(More)
We consider the problem of automatically prescribing oblique planes (short axis, 4 chamber and 2 chamber views) in Cardiac Magnetic Resonance Imaging (MRI). A concern with technologistdriven acquisitions of these planes is the quality and time taken for the total examination. We propose an automated solution incorporating anatomical features external to the(More)
Introduction: Dynamic and 4D MRI have been used to understand the functional and metabolic aspects of disease and its progression. Examples include dynamic contrast enhancement (DCE) for micro-vasculature of tumors and MR spectroscopic imaging (MRSI) for tissue bio-chemistry. The post-processing strategy for most of these protocols consists of obtaining(More)