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OBJECTIVE To assess the internal consistency and dimensionality of the Short Alcohol Dependence Data questionnaire in a general hospital sample. METHOD A cross-sectional study was carried out involving 169 randomly selected inpatients of a general hospital in São Paulo, Brazil. A Portuguese version of the 15-item Short Alcohol Dependence Data(More)
BACKGROUND There is a close relationship between the endocannabinoid system and alcoholism. This study investigated possible differential expression of cannabinoid receptors CB1 (CB1R) and CB2 (CB2R) in an outbred mice strain displaying behavioral variability to ethanol (EtOH)-induced locomotor sensitization. METHODS Male adult Swiss mice treated(More)
OBJECTIVE To adapt the Body Shape Questionnaire for use in the Brazilian population; to study the internal validity and the dimensionality of the scale when used in a non- clinical Brazilian population. METHOD A cross- sectional study was accomplished comprising 164 students in the first 3 years of the School of Medicine conveniently selected at the(More)
The article aimed to characterize pathological gambling, showing the main consequences of this disorder. Bibliographic survey on this theme was conducted, covering both national and international literature. Publications whose main findings emphasized related prevalence, social and economic costs, gambling legalization and resulting impact on public health,(More)
OBJECTIVE To explore situations, attitudes and behavior of public elementary school education supervisors concerning psychoactive substance misuse. METHODS The study was carried out in the city of São Paulo, Southeastern Brazil, in 2002. Data were collected using a semi-structured questionnaire applied to eight key informants in the administrative area(More)
Alcohol misuse is generally not detected in hospital settings. The goal of this study was to estimate the prevalence of alcohol abuse and dependence in hospitalized patients in a university hospital in Sao Paulo (Brazil). Patients were randomly selected from all hospital admissions. The final sample consisted of 169 adult inpatients. Two screening tools(More)
Introduction: The Personal Experience Screening Questionnaire (PESQ) is an instrument devised for assessing the magnitude of drug misuse among adolescents. However, its psychometric properties have not been evaluated in adolescent samples outside the United States. Objective: To assess the internal reliability and validity of the Brazilian version of the(More)
This study evaluated the semantic equivalence of the Online Cognition Scale in Brazilian Portuguese. The process included five steps: translation, back-translation, technical review, evaluation of semantic equivalence by trained professionals, and evaluation of the instrument for content understanding by a group of professionals (n = 10) and students (n =(More)
Chronic drug exposure and drug withdrawal induce expressive neuronal plasticity which could be considered as both functional and pathological responses. It is well established that neuronal plasticity in the limbic system plays a pivotal role in relapse as well as in compulsive characteristics of drug addiction. Although increases in FosB/DeltaFosB(More)