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A 1-factorisation of a graph is perfect if the union of any two of its 1-factors is a Hamiltonian cycle. Let n=p 2 for an odd prime p. We construct a family of (p − 1)/2 non-isomorphic perfect 1-factorisations of K n, n. Equivalently, we construct pan-Hamiltonian Latin squares of order n. A Latin square is pan-Hamilto-nian if the permutation defined by any… (More)

MOTIVATION
A consensus sequence for a family of related sequences is, as the name suggests, a sequence that captures the features common to most members of the family. Consensus sequences are important in various DNA sequencing applications and are a convenient way to characterize a family of molecules.
RESULTS
This paper describes a new algorithm for… (More)

The set of integers k for which there exist three latin squares of order n having precisely k cells identical, with their remaining n 2 − k cells diierent in all three latin squares, denoted by I 3 [n], is determined here for all orders n.

Cyclic m-cycle systems of order v are constructed for all m ≥ 3, and all v ≡ 1(mod 2m). This result has been settled previously by several authors. In this paper, we provide a different solution, as a consequence of a more general result, which handles all cases using similar methods and which also allows us to prove necessary and sufficient conditions for… (More)

Despite the success of conventional Sanger sequencing, significant regions of many genomes still present major obstacles to sequencing. Here we propose a novel approach with the potential to alleviate a wide range of sequencing difficulties. The technique involves extracting target DNA sequence from variants generated by introduction of random mutations.… (More)