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Since dairy cows during the transition period have multiple endocrine and metabolic changes, it is necessary to determine the reference limits of laboratory analytes in normal transition cows. Reference limits for the weeks before and after calving were determined in dairy cows. Animals that had adverse clinical outcomes after calving and cows that were(More)
OBJECTIVE To identify serum biochemical and hematologic variables, as measured in the week before parturition, that predict postpartum retention of the placenta (RP) in dairy cows. DESIGN Retrospective cohort study. ANIMALS 1,038 cows in 20 commercial dairy herds. PROCEDURES Serum concentrations of fatty acids (FAs), beta-hydroxybutyrate, cholesterol,(More)
OBJECTIVE To compare isoflurane and propofol for maintenance of anesthesia and quality of recovery in client-owned dogs with intracranial disease undergoing magnetic resonance imaging (MRI). STUDY DESIGN Prospective, randomized, clinical trial. ANIMALS Twenty-five client-owned dogs with intracranial pathology, 13 females and 12 males, ages 11 months to(More)
OBJECTIVE Gentamicin impregnated collagen sponge (GICS) can be used to treat intra-articular surgical site infections. High local concentrations of gentamicin can be reached for short periods; however the collagen vehicle may persist for much longer periods. We wished to determine the effect of sponge implantation on joint inflammation and renal function.(More)
BACKGROUND Primary immune-mediated hemolytic anemia (IMHA) is an important cause of morbidity and mortality in dogs. The mechanisms underlying autoimmune reactivity remain poorly understood. OBJECTIVE The aim of this study was to identify membrane proteins of RBCs that could be antigenic in dogs with primary IMHA. METHODS Antibodies were eluted with(More)
transmission, host response to threat and injury, pathogenic mechanisms of infectious and toxic agents, and manipulation of disturbances in health. The interaction among host, environmental, and etiologic factors in the development of disease will be highlighted. Students will learn to recognize, describe, and evaluate disturbances of health and homeostasis(More)
In humans, multiple cytokines have been linked to the development of lymphoma, and are relevant biomarkers for response to chemotherapy and prognosis. In contrast, only a few circulating cytokines have been studied in dogs with lymphoma. We prospectively enrolled thirty-one dogs newly diagnosed with multicentric lymphoma. Immunophenotype was determined by(More)
No single test is comprehensive enough to detect all of the variants of von Willebrand Disease (VWD), making determination of both concentration and function of von Willebrand Factor (VWF) important for an accurate diagnosis. The objective of the study was to validate a newly developed VWF collagen binding assay (VWF:CB) and VWF antigen enzyme-linked(More)
OBJECTIVE To systematically examine evidence surrounding definitions and reporting of data for viscoelastic testing in veterinary medicine. DESIGN Standardized, systematic evaluation of the literature, categorization of relevant articles according to level of evidence and quality, and development of consensus on conclusions for application of the concepts(More)
This article provides an overview of the complex relationship between inflammation and coagulation and a review of routinely available laboratory and point-of-care tests for the detection of inflammation and coagulopathies. In the management of cases requiring ongoing laboratory and clinical evaluation, examination of these two major pathologic processes(More)