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MOTIVATION In silico experiments in bioinformatics involve the co-ordinated use of computational tools and information repositories. A growing number of these resources are being made available with programmatic access in the form of Web services. Bioinformatics scientists will need to orchestrate these Web services in workflows as part of their analyses.(More)
SUMMARY Life sciences research is based on individuals, often with diverse skills, assembled into research groups. These groups use their specialist expertise to address scientific problems. The in silico experiments undertaken by these research groups can be represented as workflows involving the coordinated use of analysis programs and information(More)
As web service technology matures there is growing interest in exploiting workflow techniques to coordinate web services. Bioinformaticians are a user community who combine web resources to perform in <i>silico</i> experiments. These users are scientists and not information technology experts they require workflow solutions that have a low cost of entry for(More)
OBJECTIVES The GEMSS project is developing a secure Grid infrastructure through which six medical simulations services can be invoked. We examine the legal and security framework within which GEMSS operates. METHODS We provide a legal qualification to the operations performed upon patient data, in view of EU directive 95/46, when using medical(More)
MyGrid is an e-Science Grid project that aims to help biologists and bioinformaticians to perform workflow-based in silico experiments, and help them to automate the management of such workflows through personalisation, notification of change and publication of experiments. In this paper, we describe the architecture of myGrid and how it will be used by the(More)
Many areas of life sciences research involve integrating terabytes of heterogeneous, distributed and autonomous data available on the Web. The my Grid project has addressed these challenging problems by developing and applying novel grid and semantic web services technology to life science data integration, particularly genome annotation and microarray(More)
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