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PURPOSE To retrospectively evaluate the accuracy of endorectal magnetic resonance (MR) imaging in the detection and local staging of transition zone prostate cancers, with pathologic analysis serving as the reference standard, and to assess MR imaging features of these cancers. MATERIALS AND METHODS The institutional review board approved this(More)
PURPOSE To prospectively evaluate magnetic resonance (MR) imaging and MR spectroscopy for depiction of local prostate cancer recurrence after external-beam radiation therapy, with step-section pathologic findings as the standard of reference. MATERIALS AND METHODS Study received institutional approval, and written informed consent was obtained. Study was(More)
OBJECTIVE To design new models that combine clinical variables and biopsy data with magnetic resonance imaging (MRI) and MR spectroscopic imaging (MRSI) data, and assess their value in predicting the probability of insignificant prostate cancer. PATIENTS AND METHODS In all, 220 patients (cT stage T1c or T2a, prostate-specific antigen level <20 ng/mL,(More)
PURPOSE We compared the accuracy of endorectal magnetic resonance imaging (erMRI), transrectal ultrasound (TRUS) guided biopsy and digital rectal examination (DRE) for detecting the location of cancer in the prostate gland and seminal vesicles. MATERIALS AND METHODS This is a retrospective study of 106 consecutive patients with prostate cancer who were(More)
PURPOSE OF REVIEW The aim of this article is to review novel MRI and nuclear medicine methods for detecting and planning salvage treatment for prostate cancer local recurrence after radical prostatectomy or radiation therapy. RECENT FINDINGS Traditional methods for detecting local recurrence (i.e., digital rectal exam or transrectal ultrasound and digital(More)
OBJECTIVES/HYPOTHESIS Sestamibi imaging can provide critical information regarding the location of suspected parathyroid adenomas. However, this modality can be challenging to perform and interpret reliably. The impact of experience on the localizing efficacy of sestamibi scanning was assessed. STUDY DESIGN Prospective analysis of a consecutive series of(More)
PURPOSE To determine whether prostate cancer local recurrence after radiation therapy (RT) occurs at the site of primary tumor by retrospectively comparing the tumor location on pre-RT and post-RT magnetic resonance imaging (MRI) and using step-section pathology after salvage radical prostatectomy (SRP) as the reference standard. METHODS AND MATERIALS(More)
Imaging prostate cancer continues to represent a clinical challenge for both primary and recurrent disease. In the evaluation of the persistent/recurrent/metastatic prostate cancer, knowledge of cancer location (local v distant), size, and extent are essential in order to design a treatment, tailored to each patient's needs. There are evidence-based(More)
Magnetic resonance imaging (MRI) is increasingly being recognized as a valuable tool for the assessment of prostate cancer. In recent years, MRI technology has matured, image acquisition and interpretation have improved, and a multitude of clinical studies have demonstrated the potential of MRI techniques for contributing to prostate cancer care. This(More)
PURPOSE To investigate whether pretreatment endorectal magnetic resonance imaging (MRI) findings can predict biochemical relapse in patients with clinically localized prostate cancer treated with external beam radiation therapy (EBRT). METHODS AND MATERIALS Between January 2000 and January 2002, 224 patients (median age, 69 years; age range, 45-82 years)(More)