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How genes are regulated to produce the correct assortment of proteins for every cell type is a fundamental question in biology. For many genes, regulation begins at the DNA level with the use of promoter sequences to control transcription. Regulation can also occur after transcription using sequences in the 3' untranslated region (UTR) of the mRNA to affect(More)
Atrial fibrillation (AF) is the most common cardiac arrhythmia, but little is known about the molecular mechanisms associated with AF arrhythmogenesis. DNA methylation is an important epigenetic mechanism that regulates gene expression and downstream biological processes. We hypothesize that DNA methylation might play an important role in the susceptibility(More)
Selection of genes for survey We performed a literature search for proteins immunostained in the germline (http://www.textpresso.org) and obtained 102 proteins. For 75, we could derive the complete germline expression pattern (adult hermaphrodites) from the published data. Among these, we selected 5 expressed in all germ cells (from a total of 40), 5(More)
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