• Publications
  • Influence
Inhibition of Ras for cancer treatment: the search continues.
TLDR
An overview of past and ongoing strategies to inhibit oncogenic Ras in cancer is presented and genome-wide unbiased genetic screens have identified novel directions for future anti-Ras drug discovery. Expand
Analysis of the secondary structure of ITS transcripts in peritrich ciliates (Ciliophora, Oligohymenophorea): implications for structural evolution and phylogenetic reconstruction.
TLDR
This study validated for the first time a secondary structure of ITS1 and ITS2 from peritrich ciliates and demonstrated its potential in helping to resolve deep phylogenetic relationships. Expand
The All-Data-Based Evolutionary Hypothesis of Ciliated Protists with a Revised Classification of the Phylum Ciliophora (Eukaryota, Alveolata)
TLDR
The molecular dataset was expanded with representatives from 55 orders and all major lineages and the monophyly of classes Phyllopharyngea, Karyorelictea, Armophorea, Prostomatea, Plagiopylea, Colpodea and Heterotrichea are confirmed. Expand
Vorticella Linnaeus, 1767 (Ciliophora, Oligohymenophora, Peritrichia) is a grade not a clade: redefinition of Vorticella and the families Vorticellidae and Astylozoidae using molecular characters
TLDR
It is shown that Vorticella microstoma morphotypes, Astylozoon, and Opisthonecta form a well-supported, monophyletic clade, that is distinct from and basal to the family VortICEllidae containing other species of Vorticeslla. Expand
An integrative approach to phylogeny reveals patterns of environmental distribution and novel evolutionary relationships in a major group of ciliates
TLDR
Reconstruction of ancestral states revealed that peritrichs may have transitioned repeatedly from freshwater to brackish/marine/hypersaline environments and provided a model of how to elucidate evolution in the context of ecological niches in any lineage of microbial eukaryotes. Expand
Microbial Eukaryote Diversity and Activity in the Water Column of the South China Sea Based on DNA and RNA High Throughput Sequencing
TLDR
Light is shed on the diversity and activity of microbial eukaryotes in the water column of a tropical oligotrophic ocean and their potential contributions in the downward transportation of organic material from the surface ocean to the deep via the biological pump. Expand
An ITS-based phylogenetic framework for the genus Vorticella: finding the molecular and morphological gaps in a taxonomically difficult group
TLDR
Molecular systematics for this group of ciliates are moved to the infrageneric level by sequencing additional molecular markers—fast-evolving internal transcribed spacer regions—in a broad sample of 66 individual samples of 28 morphospecies of Vorticella collected from Asia, North America and Europe. Expand
Genetic Identities of Cryptic Species in the Strombidium stylifer/apolatum/oculatum Cluster, Including a Description of Strombidium rassoulzadegani n. sp.
TLDR
To assess diversity among cryptic species of the ciliate genus Strombidium, small subunit ribosomal DNA gene (SSU‐rDNA) was characterized from several lineages that had been identified previously as distinct based on the internal transcribed spacer regions of the rDNA locus. Expand
Species Boundaries in Tintinnid Ciliates: A Case Study – Morphometric Variability, Molecular Characterization, and Temporal Distribution of Helicostomella species (Ciliophora, Tintinnina)
TLDR
Analysis of the temporal distribution of species of the hyaline tintinnid Helicostomella in Jangmok Bay of Geoje Island on the south coast of Korea suggests that these two forms represent two distinct species despite their highly similar lorica morphology. Expand
Taxonomy and molecular systematics of three oligotrich (s.l.) ciliates including descriptions of two new species, Strombidium guangdongense sp. nov. and Strombidinopsis sinicum sp. nov. (Protozoa,
TLDR
In this study, the morphology of three oligotrich ciliates was investigated and the molecular phylogeny of each species based on small subunit rRNA (SSU rRNA) gene sequence data was analysed, suggesting the latter character is a synapomorphy for this group of strombidiids. Expand
...
1
2
3
4
5
...