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Potential synergistic interaction between gemcitabine (GEM) and epirubicin (EPI) in pancreatic cancer have been described previously. The maximum-tolerated dose in this trial was GEM 1000 mg m(-2) and EPI 45 mg m(-2). Median time to progression was 5.1 months and median survival time 7.4 months. This combination appears well tolerated and shows promising(More)
We present a design for the wiki-based classification of concepts within scientific and technical disclosures. Each classification code is a graphic representation of an individual entity together with related entities: the degree of similarity being apparent from what is effectively a one-dimensional ontology. A library of hyper linked graphic(More)
PURPOSE The occurrence of benign bile duct stenoses is mostly associated with prior biliary surgery, pancreatic diseases or sclerosing cholangitis. It remains a challenging problem for gastroenterologists and surgeons, especially in case the endoscopic approach is not possible. The exact role of percutaneous transhepatic stenting for these patients has not(More)
This book contains the papers that were presented on the fourth conference on Advances in Computer Chess, held at Brunel University, London in April 1984. Together with the main tournaments, this tri-annual conference is the main event in the computer chess world. The 13 contributions cover a broad spectrum of topics in computer chess, and some are(More)