CONTEXT AND OBJECTIVE
Metabolic and body compositional consequences of GH deficiency (GHD) in adults are associated with a phenotype similar to the metabolic syndrome (MetS).
PATIENTS
We assessed… (More)
BACKGROUND
GH therapy in adult patients with GH deficiency (GHD) was approved over 10 yr ago, and the indication has subsequently gained broad acceptance. The HypoCCS surveillance database is a… (More)
This study reports a comprehensive array of breast cancer statistics for Manitoba for a 40-year period. Data from the Manitoba Cancer Registry were combined with the provincial population-based… (More)
CONTEXT
Previous exposure to hypercortisolism due to Cushing's disease (CD) may adversely affect long-term metabolic and cardiovascular outcomes. In particular, metabolic and cardiovascular outcomes… (More)
Daojun Hardin, Dana Sue Erfurth, +4 authorsShlomo Melmed
2017
Background The French Safety and Appropriateness of Growth Hormone treatments in Europe (SAGhE) cohort has raised concern of increased mortality risk during follow-up into adulthood in certain… (More)
CONTEXT
GH replacement in adult GH-deficient patients may cause insulin resistance, raising concerns of potential increased risk of developing diabetes mellitus (DM).
OBJECTIVE
Our objective was to… (More)
CONTEXT
Previous studies showed improvement in impaired quality of life (QoL) in adult patients with growth hormone (GH) deficiency (GHD) who were treated with GH; improvement was sustained over a… (More)
The French Safety and Appropriateness of Growth Hormone treatments in Europe (SAGhE) cohort has raised concern of increased mortality risk during follow-up into adulthood in certain patients who had… (More)
BACKGROUND
To our knowledge, no controlled studies of the effects of long-term growth hormone replacement on fracture risk in adult patients with growth hormone deficiency exist. We assessed the… (More)
Observational studies are usually imbalanced in the factors associated with the outcome measures. Simply presenting the descriptive results or the P values from an unadjusted between-group comparison… (More)