Danya Horwath

Learn More
OBJECTIVE To evaluate independently the effect of blastomere number and degree of fragmentation on pregnancy outcome following single ETs in women with a decreased egg reserve. DESIGN Retrospective cohort analysis. SETTING In vitro fertilization center of a university-based practice. PATIENT(S) Women having a single ET related to a decreased egg(More)
Initial in vitro fertilization (IVF)-embryo transfer studies found poor fertilization and pregnancy rates following conventional fertilization of oocytes when using sperm with <4% normal morphology using strict criteria. Some consider today that sperm with only < or =5% normal morphology using strict criteria are associated with infertility. However, other(More)
PURPOSE To determine in cases of unexplained infertility whether conventional oocyte insemination vs. intracytoplasmic sperm injection results in differences in fertilization rates, frequency of failed fertilization, clinical and live delivered pregnancy rates, and implantation rates. METHODS Retrospective evaluation of these parameters in couples(More)
PURPOSE To determine if longer storage of embryos in a cryopreserved state negatively affects the chance of successful implantation following thawing and transfer. METHODS A retrospective cohort analysis of frozen-thawed embryos that had been donated to recipients. Four time periods were evaluated. RESULTS No significant decrease in pregnancy or(More)
PURPOSE Failed fertilization with ICSI in women having at least five mature oocytes retrieved is uncommon. The present study evaluated 19 such patients to determine--based on this outcome--what option they would choose next and what the outcome would be. METHODS The study requirements included females age < or = 43 and use of ejaculated sperm. RESULTS(More)
PURPOSE To determine the pregnancy rate following the exclusive transfer of twice frozen twice thawed embryos. MATERIALS AND METHODS All day 3 transfers of exclusive twice frozen-twice thawed embryos were retrospectively identified over a 13-year time-period. The cryopreservation technique used a simplified slow cool freezing protocol. Embryos could have(More)
PURPOSE To determine the pregnancy rates according to age in women failing to conceive after three previous embryo transfers or having a husband whose sperm shows a DNA fragmentation index (DFI) > 30% when performing the sperm chromatin structure assay. METHODS Women up to age 45 were included and there was no restriction for low egg reserve. Live(More)
PURPOSE To determine if cryopreservation influences pregnancy outcome following transfer. METHODS Retrospective cohort analyses of frozen embryo transfer (ET) cycles divided into five different categories according to reason for freezing. RESULTS Frozen embryos remaining as a result of failing to conceive with the previous fresh transfer or those(More)
PURPOSE To determine if top embryos require an unusual, and possibly fortuitous, combination of excellent oocyte quality and sperm, or whether some oocyte property alone leads to the formation of superior quality embryos on day 3. METHODS The embryo quality of donor oocyte recipient cycles was evaluated to find a woman who made 100% top embryos. After(More)
PURPOSE To compare the efficacy of freezing embryos at the 2 pronuclear stage vs multi-cell stage using a simplified freezing protocol with a one-step removal of the cryoprotectant. METHODS A retrospective analysis was performed. Survival, delivered pregnancy and implantation rates were compared in transfers of all embryos frozen at 2 pronuclear stage(More)