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Various magnetic resonance (MR) techniques are used to study the pathological evolution of demyelinating diseases, such as multiple sclerosis (MS). However, few studies have validated MR derived measurements with histopathology. Here, we determine the correlation of myelin water imaging, an MR measure of myelin content, with quantitative histopathologic(More)
The aim of the study was to assess the effect of recombinant human growth hormone (rhGH) on serum lipids in children treated with chronic peritoneal dialysis. We studied 26 patients aged 5–18 years, including 13 patients treated with rhGH at a dose of 1–1.1 IU/kg per week for 6 months and a control group of 13 patients. Serum total cholesterol (TC),(More)
2047 Background: Imatinib (Gleevec) is an oral tyrosine kinase inhibitor with established clinical activity in chronic myeloid leukemia & gastrointestinal stromal tumors. Imatinib also targets Kit and the platelet derived growth factor receptor (PDGFR). PDGFR inhibition may result in activity against malignancies of the breast, head & neck, prostate, and(More)
The aim of the study was to assess an effect of lipid lowering diet on serum lipids in peritoneal dialysis patients. Total cholesterol (TC) decreased after 3 months of low-fat diet from 203.7 mg/dl to 181 mg/dl, probably due to increased P/S ratio (PUFA/SFA) from 0.4 to 0.57. After another 3 months of the diet, a decrease in P/S ratio and concomitant(More)
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