Danilo Teixeira Noritomi

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OBJECTIVE Intravenous infusion of crystalloid solutions is a cornerstone of the treatment of hemorrhagic shock. However, crystalloid solutions can have variable metabolic acid-base effects, perpetuating or even aggravating shock-induced metabolic acidosis. The aim of this study was to compare, in a controlled volume-driven porcine model of hemorrhagic(More)
INTRODUCTION Oversedation frequently occurs in ICUs. We aimed to evaluate a minimal sedation policy, using sedative consumption as a monitoring tool, in a network of ICUs targeting decrement of oversedation and mechanical ventilation (MV) duration. METHODS A prospective quality improvement project was conducted in ten ICUs within a network of nonteaching(More)
OBJECTIVE The current definition of severe sepsis and septic shock includes a heterogeneous profile of patients. Although the prognostic value of hyperlactatemia is well established, hyperlactatemia is observed in patients with and without shock. The present study aimed to compare the prognosis of septic patients by stratifying them according to two(More)
EDITORIAL Ventilatory support has been a major reason for hospitalization in intensive care units (ICU) since the creation of these units, which came about precisely for that immediate need during the polio epidemic in Europe. In 1967, Ashbaugh described a series of severe cases marked by respiratory failure, cyanosis, hypoxemia refractory to oxygen therapy(More)
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