Danijela Karanović

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The effect of X-irradiation on PHA-stimulated rat lymphocytes has been investigated. The animals were exposed to doses of 100 to 800 R. Blood obtained by cardiac puncture was defibrinated and the lymphocytes sedimented by Dextraven. Lymphocytes were separated from supernatant and cultivated for three days in standard medium supplemented with rat serum and(More)
High blood pressure is the most powerful contributor to the cardiovascular morbidity and mortality, and inverse correlation between consumption of polyphenol-rich foods or beverages and incidence of cardiovascular diseases gains more importance. Reactive oxygen species plays an important role in the development of hypertension. We found that wild thyme (a(More)
The abscopal effects of high doses of X-irradiation, 6000 R given in 12 fractions locally on rat face and jaw region, upon the haematopoietic and lymphatic tissues, were studied. Haematological and pathophysiological studies were performed. Peripheral blood samples were taken after the 7th, 17th and 27th day during the course of the irradiation. 24 hours(More)
It was previously reported that PHA-incubation of a pool of peripheral-blood lymphocytes before their i.v. injection into rats submitted to total body irradiation, stimulates spleen colony formation and growth. On the same model, the present study has investigated the effect of lymphocyte preincubation with supernates obtained in short term cultures from(More)
Limited numbers of studies include research of microvibration therapy in experimental models. We examined effects of chronic vibroacustic-microvibration treatment on haemodynamics and anti-oxidative defense in experimental hypertension. Study was performed on chronically treated hypertensive and normotensive Wistar rats. Mean arterial pressure (MAP),(More)
Many studies demonstrated that angiotensin 2 type 1 receptor (AT1R) blockade accelerates renal recovery in post-ischaemic kidney but there are many controversies related to its net effect on kidney structure and function. During the past years, our research group was trying to define the pathophysiological significance of the renin–angiotensin system on(More)
The effect of total single fractionated irradiation with short time interval on haematopoietic regeneration of the bone marrow and spleen was investigated. Also, the importance of first dose, when dose of 600 R was divided in two unequal fractions with time interval of 300s was studied. The investigation was performed on 25 day old rats. The dose of 600 R(More)