Danielle Perras

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Introduction The potential advantages of the use of informatics support for applied clinical research and clinical trials seems to be evident, however their real use is very variable. In medical informatics we tend to focus on tools for patient care rather than clinical rsearch and it would seem profitable to address the question what are the bafriers to(More)
The plasma proteins have been reported to exert irreversible effects on some beta-lactams. The penems represent a class of antibiotics of great interest due to their wide spectrum of activity. However, many compounds of this class were found to be unstable in rat serum. A prototype compound, (+/-)-2-methylpenem-3-carboxylic acid (BCL-98), was selected for(More)
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