Danielle M Maclean

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Bacteriophage T4 capsid is an elongated icosahedron decorated with 155 copies of Hoc, a nonessential highly antigenic outer capsid protein. One Hoc monomer is present in the center of each major capsid protein (gp23*) hexon. We describe an in vitro assembly system which allows display of HIV antigens, p24-gag, Nef, and an engineered gp41 C-peptide trimer,(More)
In the period between April 1977 and April 1981, 105 femoropopliteal bypass grafts were performed for atherosclerotic occlusive arterial disease below the inguinal ligament. Forty-six of these were done using polytetrafluoroethylene (PTFE) and the remaining 59 using autogenous saphenous vein. In April 1982 a retrospective evaluation of the efficacy of the(More)
Radiological thrombosis was demonstrated on six occasions in the leg veins in 66 patients following the placement of 71 femoropopliteal bypass grafts. All patients received dextran 70 as prophylaxis postoperatively. The incidence was similar for grafts with the lower anastomosis either above or below the knee joint. No predisposing factors to venous(More)
The clinical records of 386 patients undergoing surgery for peripheral arterial disease during the period 1958 to 1974 were examined for patterns of wound infection. The incidence of infection in arterial reconstructive procedures was 7.4%, of which infections 2.2% were major. A high incidence of minor wound infection was found not to be of significance(More)
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