Danielle M. E. van Assema

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Background: Accumulation of amyloid-beta (Aß) in Alzheimer's disease (AD) may result from an imbalance between Aß production and Aß clearance. The mechanisms of Aß clearance from the brain are not yet fully understood. P-glycoprotein (P-gp) is an efflux pump at the blood– brain barrier (BBB) and it has been shown that P-gp is involved in Aß clearance. P-gp(More)
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