Danielle Cristina Tomaz da Silva

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BACKGROUND Obesity is defined by excessive accumulation of body fat relative to lean tissue. Studies during the last few years indicate that cardiac function in obese animals may be preserved, increased or diminished. OBJECTIVE Study the energy balance of the myocardium with the hypothesis that the increase in fatty acid oxidation and reduced glucose(More)
BACKGROUND Obesity is a risk factor for many medical complications; medical research has shown that hemodynamic, morphological and functional abnormalities are correlated with the duration and severity of obesity. OBJECTIVE Present study determined the influence of term of exposure to high-fat diet-induced obesity on myocardial collagen type I and III. (More)
BACKGROUND The activation of the beta-adrenergic system promotes G protein stimulation that, via cyclic adenosine monophosphate (cAMP), alters the structure of protein kinase A (PKA) and leads to phospholamban (PLB) phosphorylation. This protein participates in the system that controls intracellular calcium in muscle cells, and it is the primary regulator(More)
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