Daniela Moraes

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CONTEXT Curative therapy for diabetes mellitus mainly implies replacement of functional insulin-producing pancreatic beta cells, with pancreas or islet-cell transplants. However, shortage of donor organs spurs research into alternative means of generating beta cells from islet expansion, encapsulated islet xenografts, human islet cell-lines, and stem cells.(More)
CONTEXT In 2007, the effects of the autologous nonmyeloablative hematopoietic stem cell transplantation (HSCT) in 15 patients with type 1 diabetes mellitus (DM) were reported. Most patients became insulin free with normal levels of glycated hemoglobin A(1c) (HbA(1c)) during a mean 18.8-month follow-up. To investigate if this effect was due to preservation(More)
BACKGROUND Autologous haemopoietic stem-cell transplantation (HSCT) benefits patients with systemic sclerosis but has been associated with significant treatment-related mortality and failure to improve diffusion capacity of carbon monoxide (DLCO). We aimed to assess efficacy of HSCT and use of rigorous cardiac screening in this group. METHODS We assessed(More)
Mesenchymal stromal cells (MSCs) are multipotent progenitor cells used in several cell therapies. MSCs are characterized by the expression of CD73, CD90, and CD105 cell markers, and the absence of CD34, CD45, CD11a, CD19, and HLA-DR cell markers. CD90 is a glycoprotein present in the MSC membranes and also in adult cells and cancer stem cells. The role of(More)
The exponential growth of the electronic market, aggravated by the early obsolescence of electronic product, has generated an environmental problem of resource depletion and accumulation of electronic waste (e-waste). When improperly discarded, the e-waste presents risks for health and environment. From this perspective, manufacturers, distributors,(More)
The middle meningeal artery (MMA) is the largest branch of the internal maxillary artery supplying the meninges. The complex sequence of MMA development gives many opportunities for variant anatomy. Additionally, the variations in the origin of the MMA are of clinical importance when dealing with fractures of the base of the skull, epidural hematomas, and(More)
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