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Guidelines for the Care and Welfare of Cephalopods in Research –A consensus based on an initiative by CephRes, FELASA and the Boyd Group
This paper is the result of an international initiative and is a first attempt to develop guidelines for the care and welfare of cephalopods (i.e. nautilus, cuttlefish, squid and octopus) followingExpand
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Cephalopods in neuroscience: regulations, research and the 3Rs
Cephalopods have been utilised in neuroscience research for more than 100 years particularly because of their phenotypic plasticity, complex and centralised nervous system, tractability for studiesExpand
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CiC3-1a-Mediated Chemotaxis in the Deuterostome Invertebrate Ciona intestinalis (Urochordata) 1
Deuterostome invertebrates possess complement genes, and in limited instances complement-mediated functions have been reported in these organisms. However, the organization of the complementExpand
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A role for variable region-containing chitin-binding proteins (VCBPs) in host gut–bacteria interactions
A number of different classes of molecules function as structural matrices for effecting innate and adaptive immunity. The most extensively characterized mediators of adaptive immunity are theExpand
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The Gut of Geographically Disparate Ciona intestinalis Harbors a Core Microbiota
It is now widely understood that all animals engage in complex interactions with bacteria (or microbes) throughout their various life stages. This ancient exchange can involve cooperation and hasExpand
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Ancient origin of the complement system: emerging invertebrate models.
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First Identification of a Chemotactic Receptor in an Invertebrate Species: Structural and Functional Characterization of Ciona intestinalis C3a Receptor
In mammals, the bioactive fragment C3a, released from C3 during complement activation, is a potent mediator of inflammatory reactions and exerts its functional activity through the specific bindingExpand
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Immune competence of the Ciona intestinalis pharynx: complement system-mediated activity.
In the tunicate Ciona intestinalis, the ciliated pharynx, which connects the external environment to a highly developed and compartmentalized gastrointestinal system, represents the natural portal ofExpand
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IL-1 family cytokines and soluble receptors in systemic lupus erythematosus
BackgroundDysregulated production of cytokines has a critical role in systemic lupus. The aim of this work is to identify, by a comprehensive analysis of IL-1 family cytokines and receptors in serum,Expand
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Circulating levels of IL-1 family cytokines and receptors in Alzheimer’s disease: new markers of disease progression?
BackgroundAlthough the mechanisms underlying AD neurodegeneration are not fully understood, it is now recognised that inflammation could play a crucial role in the initiation and progression of ADExpand
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