Daniela Cristea

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The performance of biomaterials in biological systems is of critical importance for the development of biomedical implants and tissue engineering. Using a coating (thin film) as the interface between the bulk material and the biologic environment is one of the solutions which can potentially lead to better bioresponse, improved mechanical characteristics(More)
Dextran, pullulan, and microcrystalline cellulose were cross-linked with 1-chloro-2,3-epoxypropane and reacted with N-(1-chloroethyl)-N,N-diethylamine or N-glycidyl-N,N,N-trialkylammonium chloride in order to obtain sorbents containing tertiary amino and/or quaternary ammonium groups. In vitro equilibrium sorption of cholic acid on these sorbents was(More)
Although not endemic in the European Union and European Economic Area, shigellosis is included among the priority food- and waterborne diseases carefully surveyed by the European Centre for Disease Prevention and Control. From 2010 to 2012, 1018 cumulated confirmed shigellosis cases were reported to the European Surveillance System by Romania. This(More)
The purpose of this study was to evaluate the influence of different physico-chemical parameters on Escherichia coli susceptibility to ceftriaxone (CRO), cefotaxime (CTX), imipenem (IMP), and nalidixic acid (as marker for resistance by impermeability). The influence of chemical composition of culture medium was evaluated by the comparative assessment of(More)
New hydrogel microspheres based on crosslinked dextran, containing pendant quaternary ammonium groups with different chemical structures have been synthesized and tested as possible bile acid sorbents The in vitro sodium cholate sorption by these hydrogels has been followed in the absence or in the presence of competing anions The sorption results have(More)
Cationic dextran hydrogel microspheres with pendant quaternary ammonium groups having alkyl substituents (C(2)-C(12)) at quaternary nitrogen were synthesized. The in vitro sorption of sodium salts of four bile acids (glycocholic, cholic, taurocholic, and deoxycholic acids) with these hydrogels was studied as a function of substituent alkyl chain length and(More)
The purpose of this study was to optimize an in vitro pathogenicity model, as an alternative to Sereny test (on Guinea pigs). The study was performed on 13 Shigella spp. and 3 enteroinvasive Escherichia coli (EIEC) strains isolated in Romania between 2005 and 2007. The investigation implied the comparative evaluation between the Sereny test and Cravioto's(More)
This paperwork describes a modern control method we should use during the continuous casting. This method is based on the fuzzy logic, in order to avoid any crack inside the crystallizing apparatus. This method contains two fuzzy controllers FC0 and FC1 which, based on a set of rules established with the help of the mathematical model to the crust(More)