Daniela Berger

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OBJECTIVE To measure soluble CD40 ligand (sCD40L) in sera from patients with systemic lupus erythematosus (SLE) and to study the functional capacity of sCD40L in mediating B cell activation. METHODS A 2-site enzyme-linked immunosorbent assay (ELISA) was used to measure sCD40L in the sera of 66 SLE patients, 30 disease control patients, and 23 healthy(More)
Biofilm formation on catheters is thought to contribute to persistence of catheter-associated urinary tract infections (CAUTI), which represent the most frequent nosocomial infections. Knowledge of genetic factors for catheter colonization is limited, since their role has not been assessed using physicochemical conditions prevailing in a catheterized human(More)
The specificity of T cell help for B cell activation and differentiation is maintained by the brief expression on the T cell surface, following T cell receptor-mediated triggering, of CD40 ligand (CD40L). Interaction of T helper (Th) cell CD40L with B cell CD40 induces B cell activation, cell surface expression of activation antigens, proliferation, and(More)
This paper describes the results of the first systematic investigation of ex-mental patients residing in a large Manhattan Single Room Occupancy hotel. Utilizing a "Network Profile" questionnaire, personal interviews, and participant observation, the study focuses on the relationship of social networks to the degree of personality disturbance and the(More)
BACKGROUND Dysmenorrhoea is a common gynaecological disorder.It is treated symptomatically if it is not caused by any underlying disease. Acupuncture is successfully used for menstrual disorders but is associated with certain side effects such as pain. Laser needle acupuncture is a new, non-invasive procedure that might mimic the effects of acupuncture. (More)
CONTEXT Preventive HIV vaccines can temporarily cause uninfected individuals to have positive results on HIV testing. As preparations are underway to mount larger efficacy trials, the social risks of trial participation should be studied. OBJECTIVE To describe frequency of HIV testing and discrimination among participants in a preventive phase II HIV(More)
The role played by hemostasis in the pathogenesis of ischemic stroke is still controversial. In the present study, we looked for a possible association of ischemic stroke and high clotting activity of factor II (FII:C), factor V (FV:C), factor VII (FVII:C), factor X (FX:C) and fibrinogen. We investigated 157 non-anti-coagulated patients (86 males, 71(More)
Previous studies indicate that immunization with recombinant (r) vaccinia-human immunodeficiency virus type 1 (HIV-1) gp160 and boosting with baculovirus-derived HIV-1 rgp160 results in stronger cellular and antibody responses than those following either vaccine alone. The durability of immunity over 1 year was evaluated in 12 recipients. Both cellular and(More)
Sirs: Myocardial infarction (MI) may be complicated by life threatening cardiogenic shock (CS). Known reasons include severe ventricular dysfunction due to large myocardial necrosis or ongoing ischaemia, or severe arrhythmias. Acute mechanical complications may be caused by pericardial tamponade due to rupture of the ventricular free wall, or acute(More)
PURPOSE In chronic myelogenous leukemia (CML), leukemic stem cells (LSC) represent a critical target of therapy. However, little is known about markers and targets expressed by LSCs. The aim of this project was to identify novel relevant markers of CML LSCs. EXPERIMENTAL DESIGN CML LSCs were examined by flow cytometry, qPCR, and various bioassays. In(More)