Daniela Benedec

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Traditional remedies have a long-standing history in Cameroon and continue to provide useful and applicable tools for treating ailments. Here, the anticancer, antimicrobial and antioxidant activities of ten antioxidant-rich Cameroonian medicinal plants and of some of their isolated compounds are evaluated.The plant extracts were prepared by maceration in(More)
The aim of this work was to study the chemical composition, antioxidant and antibacterial properties of Achillea distans Waldst. et Kit. subsp. distans and Achillea distans Waldst. et Kit. subsp. alpina Rochel, from the Rodna Mountains (Romania). The identification and quantification of major phenolic compounds was performed by a HPLC-MS method. The total(More)
This study sought to carry out a screening of the polyphenols from the aerial parts of four samples of Ocimum basilicum. HPLC-MS method was used to investigate the presence of phenolic compounds in the studied samples; caftaric, cafeic, chlorogenic, p-coumaric acids and rutin were identified. The total polyphenolic content was determined by using the(More)
In the present study, six indigenous species of Lamiaceae family (Origanum vulgare L., Melissa officinalis L., Rosmarinus officinalis L., Ocimum basilicum L., Salvia officinalis L. and Hyssopus officinalis L.), have been analyzed to assess the rosmarinic acid, phenyl propane derivatives and polyphenolic contents and their antioxidant and antimicrobial(More)
New series of hydrazones 5-18 were synthesized, in good yields, by reacting 4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carbohydrazide with differently substituted benzaldehyde. The resulting compounds were characterized via elemental analysis, physico-chemical and spectral data. An antimicrobial screening was done, using Gram (+), Gram (-) bacteria(More)
The purpose of this work was to evaluate chemical constituents, antioxidant and antimicrobial activities of Artabotrys hildebrandtii, an endemic medicinal plant from Madagascar. Ethanol extracts from the leaves and stem bark were tested to evaluate DPPH free radical scavenging, using butylated hydroxytoluene and quercetin as standard antioxidants. An(More)
Salicylate-containing herbs have been used as analgesic and anti-inflammatory remedies from ancient times. In this work we performed a comparative HPLC study of salicylic derivatives in three natural products: Salicis cortex, Populi gemmae and Ulmariae folium. We have identified and measured by a new, easy and fast HPLC method both salicylic acid and(More)
Nineteen bisthiazoles were tested in order to assess their anti-inflammatory and antioxidant properties. First, we evaluated the in vitro direct antioxidant capacity of the bisthiazoles using the DPPH radical scavenging method. Then, the anti-inflammatory effect was tested in acute rat experimental inflammation by measuring the acute phase bone marrow(More)
In the context of the dangerous phenomenon of fungal resistance to the available therapies, we present here the chemical synthesis of a new series of thiazolyl-triazole Schiff bases B1-B15, which were in vitro assessed for their anti-Candida potential. Compound B10 was found to be more potent against Candida spp. when compared with the reference drugs(More)
This paper presents the quantitative and qualitative analysis of the essential oils obtained from a “Holland” cultivar of Ocimum basilicum L (basil). The vegetal material was harvested from the experimental fields of the University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca (Romania) at different times of the year: June (sample 1), August(More)