Daniel Spira

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PURPOSE Iterative reconstruction has recently been revisited as a promising concept for substantial CT dose reduction. The purpose of this study was to assess the potential benefit of sinogram affirmed iterative reconstruction (SAFIRE) in head CT by comparing objective and subjective image quality at reduced tube current with standard dose filtered back(More)
UNLABELLED The aim of this study was to investigate correlations between glucose metabolism registered by (18)F-FDG PET/CT and tumor perfusion quantified by volume perfusion CT and immunohistochemical markers Ki67 and microvessel density (MVD) in patients with non-small cell lung cancer (NSCLC). METHODS Between February 2010 and April 2011, 24 consecutive(More)
OBJECTIVE To measure perfusion in different lung cancer subtypes and compare results with histopathological/immunohistochemical results. METHODS Seventy-two consecutive untreated patients with lung cancer (40 adenocarcinomas, 20 squamous cell, and 12 small cell lung cancers) were enrolled. A 40-second volume perfusion computed tomography of the tumor bulk(More)
OBJECTIVE The purposes of this article are to provide a practical review of the spectrum of imaging findings in patients with systemic IgG4-related sclerosing disease and to address the differential diagnoses. CONCLUSION IgG4-related sclerosing disease is a systemic disorder that can involve almost any organ. The imaging findings consist of diffuse and(More)
OBJECTIVE The purpose of this article is to illustrate multitechnique imaging findings in patients with primary and secondary vasculitides involving large and medium-sized vessels and their mimics. CONCLUSION Large and medium-sized vessels are affected by many primary and secondary inflammatory disorders or mimicking conditions, often presenting similar(More)
OBJECTIVES To measure and compare the objective image quality of true noncontrast (TNC) images with virtual noncontrast (VNC) images acquired by tin-filter-enhanced, dual-source, dual-energy computed tomography (DECT) of upper abdomen. MATERIALS AND METHODS Sixty-three patients received unenhanced abdominal CT and enhanced abdominal DECT (100/140 kV with(More)
To assess the value of iodine concentration (IC) in computed tomography data acquired with 80 kVp, as a surrogate for perfusion imaging in hepatocellular carcinoma (HCC) and lymphoma by comparing iodine related attenuation (IRA) with quantitative Volume Perfusion CT (VPCT)-parameters. VPCT-parameters were compared with intra-tumoral IC at 5 time points(More)
The aim of this study was to investigate correlations between glucose metabolism as determined by [18F]FDG PET/CT and tumour perfusion as quantified by volume perfusion CT in primary tumours and mediastinal lymph nodes (MLN) of patients with non-small-cell lung cancer (NSCLC). Enrolled in the study were 17 patients with NSCLC. [18F]FDG uptake was quantified(More)
BACKGROUND Evaluation of transarterial chemoembolization (TACE) by using contrast-enhanced ultrasound (CEUS) and volume perfusion computed tomography (VPCT) as methods that display tumor vascularization. PURPOSE To assess early results of TACE in patients with hepatocellular carcinoma (HCC) using CEUS and VPCT. MATERIAL AND METHODS Twenty patients with(More)