Daniel Spector

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It is known that Escherichia coli methionine mutants can grow on both enantiomers of methionine sulfoxide (met(o)), i.e., met-R-(o) or met-S-(o), indicating the presence of enzymes in E. coli that can reduce each of these enantiomers to methionine (met). Previous studies have identified two members of the methionine sulfoxide reductase (Msr) family of(More)
In this paper we give simpler proofs of the classical continuity and lower semicontinuity theorems of Reshetnyak. 1. Main result In 1968, Reshetnyak [20] proved two important results concerning the continuity and lower semicontinuity of functionals with respect to weak-star convergence of measures. These theorems are used in a variety of areas in the(More)
It is known that reactive oxygen species can oxidize methionine residues in proteins in a non-stereospecific manner, and cells have mechanisms to reverse this damage. MsrA and MsrB are members of the methionine sulfoxide family of enzymes that specifically reduce the S and R forms, respectively, of methionine sulfoxide in proteins. However, in Escherichia(More)
for their help during my stay here at Pittsburgh. Finally, I would like to thank the Department of Mathematical Sciences at Carnegie Mellon University for creating a comfortable environment of study. In particular, I want to thank Professor William J. Hrusa for being such an understanding and generous graduate advisor. Special thanks go to my family for(More)
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