Daniel Schumacher

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Telomerase is a ribonucleoprotein complex consisting of two essential core components: a reverse transcriptase and an RNA subunit (telomerase RNA [TR]). Dysregulation of telomerase has been associated with cell immortalization and oncogenesis. Marek's disease herpesvirus (MDV) induces a malignant T cell lymphoma in chickens and harbors in its genome two(More)
The role of the products of the UL10 and the UL49.5 homologous genes of Marek's disease virus serotype 1 (MDV-1) in virus replication was investigated. Deletion of either open reading frame in an infectious bacterial artificial chromosome clone (BAC20) of MDV-1 resulted in progeny viruses that were unable to spread from cell to cell. After transfection of(More)
Group velocity control is demonstrated for x-ray photons of 14.4 keV energy via a direct measurement of the temporal delay imposed on spectrally narrow x-ray pulses. Subluminal light propagation is achieved by inducing a steep positive linear dispersion in the optical response of 57Fe Mössbauer nuclei embedded in a thin film planar x-ray cavity. The direct(More)
In the United States, the Accreditation Council for Graduate Medical Education (ACGME) has instituted a new program, the Clinical Learning Environment Review (CLER), that places focus in six important areas of the resident and fellow working and learning environment. Two of these areas are patient safety and quality improvement (QI). In their early CLER(More)
BACKGROUND International data suggest that for-profit nursing homes tend to provide lower quality than not-for-profit nursing homes. In Germany, the relationships between profit orientation, price and quality of nursing homes have not been investigated. METHODS We performed an observational study using secondary data from statutory quality audits of all(More)
Slow light effects have been measured for x rays using a cavity filled with iron nuclei, where the speed of light was reduced by a factor of 10,000. In vacuum, the propagation of photons proceeds with the same speed for each color (or frequency) of light. A laser pulse, corresponding to a broad range of frequencies, will thus propagate in vacuum without any(More)
Motivational factors that undermine the willingness of raters to be timely and candid in their evaluation of residents has not been well studied. According to expectancy theory, this motivation stems from perceptions regarding the likelihood and desirability of various consequences associated with those actions.The aim of this initial investigation is to(More)
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