Daniel Schäfer

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For the treatment of full-thickness articular cartilage lesions of the knee joint, as a result of trauma or osteochondritis dissecans, a variety of biological reconstruction techniques have been developed. Different studies, some of which were performed as randomised, prospective clinical studies, showed that the autologous chondrocyte transplantation (ACT)(More)
Aims/hypothesis. To provide a nonenzymatic sensor for glucose monitoring in subcutaneous tissue. Methods. A continuously working affinity sensor based on the glucose-dependent viscosity of a sensitive liquid containing dextran and concanavalin A has been designed by arranging a microdialysis probe, two flow-resisting capillaries and two pressure transducers(More)
BACKGROUND Bednar's aphthae can still be found in newborn infants but have nearly disappeared from recent paediatric literature. OBJECTIVES To find out the incidence of Bednar's aphthae among newborn infants during the first week of life and the factors associated with the ulcers. METHODS Clinical findings and statistical data were documented of 1,654(More)
Senectus ipsa morbus est ... : Jacob Hutter (1708-1768) used this provocative hypothesis to draw attention to his doctoral thesis of the same title which was published in 1732 at the University of Halle in Central Germany. Hutter was an otherwise practically unknown figure, who later worked in his native Transylvania as a doctor and pharmacist. His(More)
Age-related memory loss was a marginal issue in medical discussions during early modern times and until well into the second half of the 17th century. There are many possible explanations: the lack of similar traditions in antiquity and in the Middle Ages, insufficient physiological and morphological knowledge of the brain, and the underlying conflict(More)
Literary and medical writers have written about elderly people--their health, constitution, and treatment--since the dawn of history. The dramatic demographic changes that have taken place within industrial nations in recent times have certainly imparted this theme with a heretofore-unknown explosiveness. Joannes Stobaios' (5th c.) three chapters "On old(More)
One cannot have an idea of this multifaceted theme without its medical and cultural-historical background. After a history of several thousand years as a remedy and consumer good, around 1800 this poppy drug was in the focus of public attention due to Brownianism, at first as an often self-prescribed unspecific remedy against physical and mental pain. Many(More)
Dass nicht nur medizinische Konzepte von Krankheit und Gesundheit sich in deutlichem Wandel befinden, sondern – in Wechselwirkung dazu – auch entsprechende gesellschaftliche und religiöse Deutungen, ist ein Thema, das derzeit in zahlreichen wissenschaftlichen Abhandlungen teils fachspezifisch [1], teils interdisziplinär [2, 3] erörtert wird. Dennoch mag es(More)