Daniel Raine

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This study compared the efficacy, tolerability, and safety of fluvoxamine, imipramine, and placebo in the treatment of panic disorder with or without agoraphobia. Fifty-four outpatients participated in the randomized, double-blind trial as part of a multicenter trial. After meeting inclusion criteria and completing screening requirements (e.g., laboratory(More)
BACKGROUND Successful termination of atrial fibrillation (AF) during catheter ablation (CA) is associated with arrhythmia-free follow-up. Preablation factors such as mean atrial fibrillation cycle length (AFCL) predict the likelihood of AF termination during ablation but recurring patterns and AFCL stability have not been evaluated. OBJECTIVE To(More)
BACKGROUND Lead V1 is routinely analysed due to its large amplitude AF waveform. V1 correlates strongly with right atrial activity but only moderately with left atrial activity. Posterior lead V9 correlates strongest with left atrial activity. AIMS (1) To establish whether surface dominant AF frequency (DAF) calculated using principal component analysis(More)
Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. As catheter ablation (CA) is increasingly becoming the preferred treatment, identifying predictors of CA outcome is important to assist clinical decision making. Previous studies have explored spectral and nonlinear indices. However, a comparative analysis of indices from(More)
BACKGROUND Non-invasive tools to help identify patients likely to benefit from catheter ablation (CA) of atrial fibrillation (AF) would facilitate personalised treatment planning. AIM To investigate atrial waveform organisation through recurrence plot indices (RPI) and their ability to predict CA outcome. METHODS One minute 12-lead ECG was recorded(More)
OBJECTIVE To assess the effect of catheter ablation on atrial fibrillation (AF) symptoms and quality of life (QoL). METHODS Patients with AF scheduled for ablation were recruited. Pulmonary vein isolation (PVI) was performed and complex fractionated atrial electrogram (CFAE)±linear ablation undertaken in patients in AF despite PVI. QoL and AF symptoms(More)
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