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The incidence of joint fractures is increasing and has become one of the major health problems in developed countries. Our low-cost motivated rehabilitation system enables clinicians to prescribe, demonstrate and monitor patient rehabilitation protocols during and between clinical visits. With its unique biofeedback feature it is useful for continuous(More)
The dopaminergic system plays an important role in the etiology of schizophrenia, and most antipsychotic drugs exert their functions by blocking dopamine D(2) receptors (D(2)Rs). Since the signaling strength mediated by D(2)Rs is regulated by internalization and degradation processes, it is crucial to identify molecules that modulate D(2)R localization at(More)
—The computer science classes in China's institutions of higher education often have large numbers of students. In addition , many institutions offer " blended " classes that include both on-campus and online students. These large blended classrooms have long suffered from a lack of interactivity. Many online classes simply provide recorded instructor(More)
and the British Journal of Educational Technology. She has also published book chapters on engaged learning in online problem solving, Cybergogy for interactive learning online, informal learning via the Internet, and effective learning in multicultural and multilingual classrooms. (17 000 students). Shen's research and development specialty focus on(More)
Proper classification of action potentials from extracellular recordings is essential for making an accurate study of neuronal behavior. Many spike sorting algorithms have been presented in the technical literature. However, no comparative analysis has hitherto been performed. In our study, three widely-used publicly-available spike sorting algorithms(More)
Approximate Entropy (ApEn) and Sample Entropy (SampEn) have proven to be a valuable analyzing tool for a number of physiological signals. However, the characterization of these metrics is still lacking. We applied ApEn and SampEn to body temperature time series recorded from patients in critical state. This study was aimed at finding the optimal analytical(More)
Mobile devices allow on-the-go people to access a world of digital information via the Internet from any location. Mobile learners, who are marked by a high degree of physical mobility, frequently use these devices to find just-in-time information about their environment. This constant connection to computer-mediated information about products, stores,(More)
In this work, we address the problem of fully automated QT-interval measurement. The method is based on detecting the Q and T points via gradient method accordingly to the beat morphology. Development and validation of the algorithm has been done using the PTB Diagnostic ECG Database prepared for Computers in Cardiology Challenge 2006. RR analysis is used(More)
We describe a novel statistical model of pressure signals that incorporates the effects of respiration on arterial (ABP) and intracranial pressure (ICP). This model can be used to synthesize pulsatile ABP and ICP signals with similar time, frequency, and variability characteristics of real pressure signals. These synthetic signals can be used during the(More)
There is evidence that rotors could be drivers that maintain atrial fibrillation. Complex fractionated atrial electrograms have been located in rotor tip areas. However, the concept of electrogram fractionation, defined using time intervals, is still controversial as a tool for locating target sites for ablation. We hypothesize that the fractionation(More)