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Many statistical methods rely on numerical optimization to estimate a model's parameters. Unfortunately, conventional algorithms sometimes fail. Even when they do converge, there is no assurance that they have found the global, rather than a local, optimum. We test a new optimization algorithm, simulated annealing, on four econometric problems and compare(More)
What makes us become aware? A popular hypothesis is that if cortical neurons fire in synchrony at a certain frequency band (gamma), we become aware of what they are representing. We tested this hypothesis adopting brain-imaging techniques with good spatiotemporal resolution and frequency-specific information. Specifically, we examined the degree to which(More)
PURPOSE It is widely believed that physical restraint use causes mental and physical health decline in nursing home residents. Yet few studies exist showing an association between restraint initiation and health decline. In this research, we examined whether physical restraint initiation is associated with subsequent lower physical or mental health. (More)
In the last 18 months, wearable devices, such as wristbands, smartwatches, eyewear, wearable bio-monitors, and the complementary services that support them have become the focus of much speculation and anticipation. Companies as varied as large original equipment manufacturers (OEMs), mobile network operators (MNOs), health insurers and service providers(More)
Employment growth in the U.S. is increasingly concentrated among jobs that require both complex cognitive skills and social-emotional competencies. This paper examines the degree to which teachers help students develop these new fundamental skills needed to succeed in the labor market. We leverage data from the Measures of Effective Teaching Project to(More)
The complication of intestinal haemorrhage in a patientwithmeningococcal septicaemiais described. The patientpresentedwithhaemodynamic instability associated with melaena within an intensive care unit. Upper and lower gastrointestinal endoscopy and angiography failed to localise the source of bleeding. At laparotomy, an isolated small bowel lesion was(More)
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