Daniel McGee

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PURPOSE To determine associations between retinopathy status and detailed serum lipoprotein subclass profiles in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study (DCCT/EDIC) cohort. METHODS Persons with type 1 diabetes (440 women, 548 men) from the DCCT/EDIC cohort were studied. Retinopathy was(More)
The Cox proportional hazards model is widely used for analyzing associations between risk factors and occurrences of events. One of the essential requirements of defining Cox proportional hazards model is the choice of a unique and well-defined time scale. Two time scales are generally used in epidemiological studies: time-on-study and chronological age.(More)
SUMMARY The Cox proportional hazards model is routinely used to determine the time until an event of interest. Two time scales are used in practice: time-on-study and chronological age. The former is the most frequently used time scale both in clinical studies and longitudinal observation studies. However, there is no general consensus about which time(More)
Based on the 40-year follow-up of the Framingham Heart Study (FHS), we used logistic regression models to demonstrate that different designs of an observational study may lead to different results about the association between BMI and all-cause mortality. We also used dynamic survival models to capture the time-varying relationships between BMI and(More)
SUMMARY The Cox proportional hazards model is widely used in time-to-event analysis. Two time scales are used in practice: time-on-study and chronological age. The former is the most frequently used time scale both in clinical studies and longitudinal observation studies. There is no general consensus about which time scale is the best. It has been asserted(More)
The Graduate School has verified and approved the above-named committee members, and certifies that the dissertation has been approved in accordance with the university requirements. ii I want to dedicate this work to my mom and dad. They taught me how to work hard to achieve the goals that I set for myself. With their wise words they always encourage me to(More)
Committee Member The Graduate School has verified and approved the above-named committee members, and certifies that the dissertation has been approved in accordance with the university requirements. ii To my husband, Jamiu T. Williams, your love speaks and my heart listens. Thank you so very much for understanding my long working hours and my continuous(More)
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