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Previous studies in metabotropic glutamate 5 receptor (mGlu5 receptor) deficient mice have indicated the importance of this receptor in the self-administration of cocaine and locomotor sensitisation(More)
Preclinical evidence suggests an important role of the brain orexin system in behaviours related to drug addiction. This study aimed at assessing the effect of the orexin-1 receptor antagonist(More)
Rationale: Evidence has implicated the nucleus accumbens (NAcc) in drug-seeking and -taking behaviour. However, the importance of the "core" and "shell" subdivisions of the NAcc in heroin-seeking and(More)
The present study examined the effects of the acute intraperitoneal (i.p.) administration of the selective dopamine (DA) D(3) receptor antagonist SB-277011A (10, 20 or 30 mg/kg i.p.) on the oral(More)