Daniel M. C. Domine

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The family of adaptive resonance theory (ART) based systems concerns distinct artificial neural networks for unsupervised and supervised clustering analysis. Among them, the ART 2-A paradigm presents numerous strengths for data analysis. After a rapid presentation of the ART 2-A theory and algorithmic information, the usefulness of this neural network for(More)
Drug discovery programs frequently target members of the human kinome and try to identify small molecule protein kinase inhibitors, primarily for cancer treatment, additional indications being increasingly investigated. One of the challenges is controlling the inhibitors degree of selectivity, assessed by in vitro profiling against panels of protein(More)
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